ACHIEVEMENTS

研究業績

2024年

  • Matsumoto M.; Matsushita K.; Hane M.; Wen C.; Kurematsu C.; Ota H.; Bang Nguyen H.; Quynh Thai T.; Herranz-Pérez V.; Sawada M.; Fujimoto K.; García-Verdugo J.M.; Kimura K.D.; Seki T.; Sato C.; Ohno N.; Sawamoto K.

    Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function

    EMBO Molecular Medicine

    https://doi.org/10.1038/s44321-024-00073-7

     

  • Hayashi M.; Yonetamari J.; Muto Y.; Tanaka K.

    Complete genome sequence of Peptostreptococcus porci isolated from porcine endocarditis in Japan

    Microbiology Resource Announcements

    https://doi.org/10.1128/mra.00201-24

  • Tokoro Y.; Nagae M.; Nakano M.; Harduin-Lepers A.; Kizuka Y.

    LacdiNAc synthase B4GALNT3 has a unique PA14 domain and suppresses N-glycan capping

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2024.107450

  • Hayashi Y.; Okumura H.; Arioka Y.; Kushima I.; Mori D.; Lo T.; Otgonbayar G.; Kato H.; Nawa Y.; Kimura H.; Aleksic B.; Ozaki N.

    Analysis of human neuronal cells carrying ASTN2 deletion associated with psychiatric disorders

    Translational Psychiatry

    https://doi.org/10.1038/s41398-024-02962-4

     

  • Kusumi A.; Tsunoyama T.A.; Suzuki K.G.N.; Fujiwara T.K.; Aladag A.

    Transient, nano-scale, liquid-like molecular assemblies coming of age

    Current Opinion in Cell Biology

    https://doi.org/10.1016/j.ceb.2024.102394

  • Hirata Y.; Takemori H.; Furuta K.; Kamatari Y.O.; Sawada M.

    Ferroptosis induces nucleolar stress as revealed by live-cell imaging using thioflavin T

    Current Research in Pharmacology and Drug Discovery

    https://doi.org/10.1016/j.crphar.2024.100196

  • Nakayama A.; Watanabe M.; Yamashiro R.; Kuroyanagi H.; Matsuyama H.J.; Oshima A.; Mori I.; Nakano S.

    A hyperpolarizing neuron recruits undocked innexin hemichannels to transmit neural information in Caenorhabditis elegans

    Proceedings of the National Academy of Sciences of the United States of America

    https://doi.org/10.1073/pnas.2406565121

  • Iwata M.; Kawabata R.; Morimoto N.; Takeuchi R.F.; Sakaguchi T.; Irie T.; Osakada F.

    Evolutionary engineering and characterization of Sendai virus mutants capable of persistent infection and autonomous production

    Frontiers in Virology

    https://doi.org/10.3389/fviro.2024.1363092

  • Fujioka Y.; Kawai K.; Endo K.; Ishibashi M.; Iwade N.; Tuerde D.; Kaibuchi K.; Yamashita T.; Yamanaka A.; Katsuno M.; Watanabe H.; Sobue G.; Ishigaki S.

    Stress-impaired reward pathway promotes distinct feeding behavior patterns

    Frontiers in Neuroscience

    https://doi.org/10.3389/fnins.2024.1349366

  • Harada A.; Kunii M.; Kurokawa K.; Sumi T.; Kanda S.; Zhang Y.; Nadanaka S.; Hirosawa K.M.; Tokunaga K.; Tojima T.; Taniguchi M.; Moriwaki K.; Yoshimura S.-I.; Yamamoto-Hino M.; Goto S.; Katagiri T.; Kume S.; Hayashi-Nishino M.; Nakano M.; Miyoshi E.; Suzuki K.G.N.; Kitagawa H.; Nakano A.

    Dynamic movement of the Golgi unit and its glycosylation enzyme zones

    Nature Communications

    https://doi.org/10.1038/s41467-024-48901-1

  • Fujita S.; Sugio Y.; Kawamura T.; Yamagami R.; Oka N.; Hirata A.; Yokogawa T.; Hori H.

    ArcS from Thermococcus kodakarensis transfers L-lysine to preQ0 nucleoside derivatives as minimum substrate RNAs

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2024.107505

  • Hanamatsu H.; Yokota I.; Kurogochi M.; Akasaka-Manya K.; Miura N.; Manya H.; Endo T.; Nishikaze T.; Furukawa J.-I.; Tanaka K.

    Direct derivatization of sialic acids and mild β-elimination for linkage-specific sialyl O-glycan analysis

    Analytica Chimica Acta

    https://doi.org/10.1016/j.aca.2024.342945

  • Fabiano M.; Oikawa N.; Kerksiek A.; Furukawa J.-I.; Yagi H.; Kato K.; Schweizer U.; Annaert W.; Kang J.; Shen J.; Lütjohann D.; Walter J.

    Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function

    International Journal of Molecular Sciences

    https://doi.org/10.3390/ijms25105417

  • Yanaka S.; Kodama A.; Nishiguchi S.; Fujita R.; Shen J.; Boonsri P.; Sung D.; Isono Y.; Yagi H.; Miyanoiri Y.; Uchihashi T.; Kato K.

    Identification of potential C1-binding sites in the immunoglobulin CL domains

    International Immunology

    https://doi.org/10.1093/intimm/dxae017

     

  • Imaeda M.; Tanaka S.; Oya-Ito T.; Uematsu M.; Fujigaki H.; Saito K.; Ando M.; Ozaki N.

    Secondary carnitine deficiency during refeeding in severely malnourished patients with eating disorders: a retrospective cohort study

    Journal of Eating Disorders

    https://doi.org/10.1186/s40337-024-01054-4

  • Kikuchi H.; Hieno A.; Suga H.; Masuya H.; Uematsu S.; Kageyama K.

    New species Pythium amaminum sp. nov. isolated from river water on Amami Island in Japan

    Mycoscience

    https://doi.org/10.47371/MYCOSCI.2024.02.004

     

     

  • Hashimoto Y.; Kawade H.; Bao W.; Morii S.; Nakano M.; Nagae M.; Murakami R.; Tokoro Y.; Nakashima M.; Cai Z.; Isaji T.; Gu J.; Nakajima K.; Kizuka Y.

    The K346T mutant of GnT-III bearing weak in vitro and potent intracellular activity

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2024.130663

  • Yoshida Y.; Niimi Y.; Fushihara D.; Katakura H.; Fukui R.; Murase H.; Tomoike F.; Hashiya F.; Murakami T.; Kodama E.N.; Suzuki T.; Yasukawa K.; Kimura Y.; Abe H.

    2′-β-Methylselenyl nucleos(t)ide analogs as reverse transcriptase inhibitors against diverse HIV mutants

    Bioorganic and Medicinal Chemistry

    https://doi.org/10.1016/j.bmc.2024.117813

  • Kizuka Y.

    Regulation of intracellular activity of N-glycan branching enzymes in mammals

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2024.107471

     

  • Noda N.; Nomura K.; Takahashi N.; Hashiya F.; Abe H.; Matsuura T.

    Slow Freeze-Thaw Cycles Enhanced Hybridization of Kilobase DNA with Long Complementary Sticky Ends

    ChemSystemsChem

    https://doi.org/10.1002/syst.202400025

  • Hagino R.; Kuwabara R.; Komura N.; Imamura A.; Ishida H.; Ando H.; Tanaka H.-N.

    Protecting-Group-Free Synthesis of ADP-Ribose and Dinucleoside Di-/Triphosphate Derivatives via P(V)-P(V) Coupling Reaction

    Chemistry – A European Journal

    https://doi.org/10.1002/chem.202401302

     

  • Watanabe S.; Amporndanai K.; Awais R.; Latham C.; Awais M.; O’Neill P.M.; Yamanaka K.; Hasnain S.S.

    Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement

    Scientific Reports

    https://doi.org/10.1038/s41598-024-62903-5

     

  • Mori D.; Inami C.; Ikeda R.; Sawahata M.; Urata S.; Yamaguchi S.T.; Kobayashi Y.; Fujita K.; Arioka Y.; Okumura H.; Kushima I.; Kodama A.; Suzuki T.; Hirao T.; Yoshimi A.; Sobue A.; Ito T.; Noda Y.; Mizoguchi H.; Nagai T.; Kaibuchi K.; Okabe S.; Nishiguchi K.; Kume K.; Yamada K.; Ozaki N.

    Mice with deficiency in Pcdh15, a gene associated with bipolar disorders, exhibit significantly elevated diurnal amplitudes of locomotion and body temperature

    Translational Psychiatry

    https://doi.org/10.1038/s41398-024-02952-6

     

     

  • Retnosari R.; Ali A.H.; Zainalabidin S.; Ugusman A.; Oka N.; Latip J.

    The recent discovery of a promising pharmacological scaffold derived from carvacrol: A review

    Bioorganic and Medicinal Chemistry Letters

    https://doi.org/10.1016/j.bmcl.2024.129826

     

     

  • Ghose A.; Nuzelu V.; Gupta D.; Kimoto H.; Takashima S.; Harlin E.W.; SS S.; Ueda H.; Koketsu M.; Rangan L.; Mitra S.

    Micropollutants (ciprofloxacin and norfloxacin) remediation from wastewater through laccase derived from spent mushroom waste: Fate, toxicity, and degradation

    Journal of Environmental Management

    https://doi.org/10.1016/j.jenvman.2024.121857

     

     

  • Tang Y.-H.; Leng J.-X.; Yang G.; Gao X.-D.; Liu Y.-S.; Fujita M.

    Production of CA125 with Tn antigens using a glycosylphosphatidylinositol anchoring system

    Journal of Biochemistry

    https://doi.org/10.1093/jb/mvae019

     

     

  • Sei H.; Hirade N.; Kamiya K.; Nakashima F.; Yoshitake J.; Kano K.; Mishiro-Sato E.; Kikuchi R.; Uchida K.; Shibata T.

    Isocitrate dehydrogenase 1 upregulation in urinary extracellular vesicles from proximal tubules of type 2 diabetic rats

    FASEB Journal

    https://doi.org/10.1096/fj.202400371R

     

  • Masuda R.; Ohira N.; Kitaguchi K.; Yabe T.

    Novel role of homogalacturonan region of pectin in disrupting the interaction between fibronectin and integrin β1

    Carbohydrate Polymers

    https://doi.org/10.1016/j.carbpol.2024.122122

  • Oka Y.; Nakazawa Y.; Shimada M.; Ogi T.

    Endogenous aldehyde-induced DNA–protein crosslinks are resolved by transcription-coupled repair

    Nature Cell Biology

    https://doi.org/10.1038/s41556-024-01401-2

  • Tomida S.; Nagae M.; Kizuka Y.

    Corrigendum to “Distinctive domains and activity regulation of core fucosylation enzyme FUT8” [BBA General Subjects 1868 (2024)/130561] (BBA – General Subjects (2024) 1868(4), (S0304416524000047), (10.1016/j.bbagen.2024.130561))

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2024.130615

     

  • Mukoyama N.; Nishio N.; Kimura H.; Tokura T.; Kishi S.; Ogasawara K.; Tsuzuki H.; Yokoi S.; Wada A.; Shigeyama M.; Ozaki N.; Fujimoto Y.; Sone M.

    Anxiety, depression and quality of life in patients with head and neck cancer undergoing laryngectomy: A long-term prospective evaluation

    International Journal of Language and Communication Disorders

    https://doi.org/10.1111/1460-6984.13036

     

  • Yamaguchi Y.; Ishii K.; Koizumi S.; Sakaue H.; Maruno T.; Fukuhara M.; Shibuya R.; Tsunaka Y.; Matsushita A.; Bandoh K.; Torisu T.; Murata-Kishimoto C.; Tomioka A.; Mizukado S.; Kaji H.; Kashiwakura Y.; Ohmori T.; Kuno A.; Uchiyama S.

    Glycosylation of recombinant adeno-associated virus serotype 6

    Molecular Therapy Methods and Clinical Development

    https://doi.org/10.1016/j.omtm.2024.101256

  • Nakagawa Y.; Fujii M.; Ito N.; Ojika M.; Akase D.; Aida M.; Kinoshita T.; Sakurai Y.; Yasuda J.; Igarashi Y.; Ito Y.

    Molecular basis of N-glycan recognition by pradimicin a and its potential as a SARS-CoV-2 entry inhibitor

    Bioorganic and Medicinal Chemistry

    https://doi.org/10.1016/j.bmc.2024.117732

  • Oishi M.; Shinjo K.; Takanari K.; Muraoka A.; Suzuki M.M.; Kanbe M.; Higuchi S.; Ebisawa K.; Hashikawa K.; Kamei Y.; Kondo Y.

    Exclusive expression of KANK4 promotes myofibroblast mobility in keloid tissues

    Scientific Reports

    https://doi.org/10.1038/s41598-024-59293-z

  • Sonobe R.; Yang P.; Suzuki M.M.; Shinjo K.; Iijima K.; Nishiyama N.; Miyata K.; Kataoka K.; Kajiyama H.; Kondo Y.

    Long noncoding RNA TUG1 promotes cisplatin resistance in ovarian cancer via upregulation of DNA polymerase eta

    Cancer Science

    https://doi.org/10.1111/cas.16150

  • Hagino R.; Komura N.; Imamura A.; Ishida H.; Ando H.; Tanaka H.-N.

    Direct and Stereoselective Protecting-Group-Free N-ADP-Ribosylation through Traceless Staudinger Ligation

    European Journal of Organic Chemistry

    https://doi.org/10.1002/ejoc.202400251

     

  • Uchihashi T.; Nishizawa Y.

    Application of high-speed atomic force microscopy in visualizing the dynamics of synthetic polymers

    Japanese Journal of Applied Physics

    https://doi.org/10.35848/1347-4065/ad33f2

  • Shiina T.; Suzuki Y.; Horii K.; Sawamura T.; Yuki N.; Horii Y.; Shimizu Y.

    Purinergic inhibitory regulation of esophageal smooth muscle is mediated by P2Y receptors and ATP-dependent potassium channels in rats

    The journal of physiological sciences : JPS

    https://doi.org/10.1186/s12576-024-00916-5

     

     

  • Lee C.-H.; Saw J.-E.; Chen E.H.-L.; Wang C.-H.; Uchihashi T.; Chen R.P.-Y.

    The Positively Charged Cluster in the N-terminal Disordered Region may Affect Prion Protein Misfolding: Cryo-EM Structure of Hamster PrP(23–144) Fibrils

    Journal of Molecular Biology

    https://doi.org/10.1016/j.jmb.2024.168576

     

  • Uno K.; Tsukioka K.; Sakata H.; Inoue-Hirakawa T.; Matsui Y.

    Evaluating Desk-Assisted Standing Techniques for Simulated Pregnant Conditions: An Experimental Study Using a Maternity-Simulation Jacket

    Healthcare (Switzerland)

    https://doi.org/10.3390/healthcare12090931

  • Kondo Y.; Li Y.; Okajima T.

    Efficient Escorting Strategy for Aggregation-Prone Notch EGF Repeats with Sparcl1

    Molecules

    https://doi.org/10.3390/molecules29051031

     

     

     

  • Nomura K.; Onda K.; Murase H.; Hashiya F.; Ono Y.; Terai G.; Oka N.; Asai K.; Suzuki D.; Takahashi N.; Hiraoka H.; Inagaki M.; Kimura Y.; Shimizu Y.; Abe N.; Abe H.

    Development of PCR primers enabling the design of flexible sticky ends for efficient concatenation of long DNA fragments

    RSC Chemical Biology

    https://doi.org/10.1039/d3cb00212h

     

     

  • Mannen K.; Nagata T.; Rozenberg A.; Konno M.; del Carmen Marín M.; Bagherzadeh R.; Béjà O.; Uchihashi T.; Inoue K.

    Multiple Roles of a Conserved Glutamate Residue for Unique Biophysical Properties in a New Group of Microbial Rhodopsins Homologous to TAT Rhodopsin

    Journal of Molecular Biology

    https://doi.org/10.1016/j.jmb.2023.168331

     

  • Liu Y.; Li R.; Zhang Y.; Jiao S.; Xu T.; Zhou Y.; Wang Y.; Wei J.; Du W.; Fujita M.; Du Y.; Wang Z.A.

    Unveiling the inverse antimicrobial impact of a hetero-chitooligosaccharide on Candida tropicalis growth and biofilm formation

    Carbohydrate Polymers

    https://doi.org/10.1016/j.carbpol.2024.121999

     

  • Mori D.; Ikeda R.; Sawahata M.; Yamaguchi S.; Kodama A.; Hirao T.; Arioka Y.; Okumura H.; Inami C.; Suzuki T.; Hayashi Y.; Kato H.; Nawa Y.; Miyata S.; Kimura H.; Kushima I.; Aleksic B.; Mizoguchi H.; Nagai T.; Nakazawa T.; Hashimoto R.; Kaibuchi K.; Kume K.; Yamada K.; Ozaki N.

    Phenotypes for general behavior, activity, and body temperature in 3q29 deletion model mice

    Translational Psychiatry

    https://doi.org/10.1038/s41398-023-02679-w

     

  • Kondo Y.; Jing W.; Xia L.

    Site-1 Protease Deficiency Causes Human Skeletal Dysplasia

    Trends in Glycoscience and Glycotechnology

    https://doi.org/10.4052/tigg.2309.1E

     

     

     

  • Mubuchi A.; Takechi M.; Nishio S.; Matsuda T.; Itoh Y.; Sato C.; Kitajima K.; Kitagawa H.; Miyata S.

    Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons

    eLife

    https://doi.org/10.7554/eLife.92342

     

     

  • Homan K.; Onodera T.; Hanamatsu H.; Furukawa J.-I.; Momma D.; Matsuoka M.; Iwasaki N.

    Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis

    eLife

    https://doi.org/10.7554/eLife.92275

     

  • Kaminogo K.; Yamaguchi S.; Tokura T.; Kimura H.; Kishi S.; Ichimura N.; Yamamoto N.; Ohara G.; Chen H.; Ozaki N.; Ikeda M.; Hibi H.

    Predictors of anxiety and depression in patients with oral cancer undergoing radical resection with reconstructive surgery

    Oral Oncology Reports

    https://doi.org/10.1016/j.oor.2024.100295

     

     

  • Funahashi R.; Matsuura F.; Ninomiya M.; Okabe S.; Takashima S.; Tanaka K.; Nishina A.; Koketsu M.

    Hybrid pharmacophore design and synthesis of donepezil-inspired aurone derivative salts as multifunctional acetylcholinesterase inhibitors

    Bioorganic Chemistry

    https://doi.org/10.1016/j.bioorg.2024.107229

     

  • Kaido M.; Yasuda M.; Hayashi M.; Ohashi H.; Ohta H.; Akai Y.; Tanaka K.; Deguchi T.

    The performance of a Fully Automated Urine Particle Analyzer, Sysmex UF-5000, in detecting fastidious bacteria in urine samples

    Journal of Microbiological Methods

    https://doi.org/10.1016/j.mimet.2024.106913

     

  • Huang L.; Kondo Y.; Cao L.; Han J.; Li T.; Zuo B.; Yang F.; Li Y.; Ma Z.; Bai X.; Jiang M.; Ruan C.; Xia L.

    Novel GNE missense variants impair de novo sialylation and cause defective angiogenesis in the developing brain in mice

    Blood Advances

    https://doi.org/10.1182/bloodadvances.2023011490

     

     

  • Wang B.; Wang Y.; Zhou X.; Gao X.-D.; Fujita M.; Li Z.

    Highly efficient expression of Rasamsonia emersonii lipase in Pichia pastoris: characterization and gastrointestinal simulated digestion in vitro

    Journal of the Science of Food and Agriculture

    https://doi.org/10.1002/jsfa.13390

     

     

     

  • Sakuma K.; Koike R.; Ota M.

    Dual-wield NTPases: A novel protein family mined from AlphaFold DB

    Protein Science

    https://doi.org/10.1002/pro.4934

     

     

  • Lo T.; Kushima I.; Kimura H.; Aleksic B.; Okada T.; Kato H.; Inada T.; Nawa Y.; Torii Y.; Yamamoto M.; Kimura R.; Funabiki Y.; Kosaka H.; Numata S.; Kasai K.; Sasaki T.; Yokoyama S.; Munesue T.; Hashimoto R.; Yasuda Y.; Fujimoto M.; Usami M.; Itokawa M.; Arai M.; Ohi K.; Someya T.; Watanabe Y.; Egawa J.; Takahashi T.; Suzuki M.; Yamasue H.; Iwata N.; Ikeda M.; Ozaki N.

    Association between copy number variations in parkin (PRKN) and schizophrenia and autism spectrum disorder: A case–control study

    Neuropsychopharmacology Reports

    https://doi.org/10.1002/npr2.12370

     

     

     

     

  • Tsukamoto Y.; Tsukamoto N.; Saiki W.; Tashima Y.; Furukawa J.-I.; Kizuka Y.; Narimatsu Y.; Clausen H.; Takeuchi H.; Okajima T.

    Characterization of galactosyltransferase and sialyltransferase genes mediating the elongation of the extracellular O-GlcNAc glycans

    Biochemical and Biophysical Research Communications

    https://doi.org/10.1016/j.bbrc.2024.149610

  • Huang C.; Seino J.; Honda A.; Fujihira H.; Wu D.; Okahara K.; Kitazume S.; Nakaya S.; Kitajima K.; Sato C.; Suzuki T.

    Rat hepatocytes secrete free oligosaccharides

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2024.105712

     

     

     

     

  • Yosilia R.; Feng W.; Hieno A.; Otsubo K.; Kusunoki M.; Suga H.; Kageyama K.

    First report of crown rot on lettuce caused by Phytophthora crassamura in Japan

    Journal of General Plant Pathology

    https://doi.org/10.1007/s10327-023-01163-z

     

     

  • Tomida S.; Nagae M.; Kizuka Y.

    Distinctive domains and activity regulation of core fucosylation enzyme FUT8

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2024.130561

     

  • Ohashi S.; Nakamura M.; Acharyya S.; Inagaki M.; Abe N.; Kimura Y.; Hashiya F.; Abe H.

    Development and Comparison of 4-Thiouridine to Cytidine Base Conversion Reaction

    ACS Omega

    https://doi.org/10.1021/acsomega.3c08516

     

     

     

  • Shintani Y.; Katagiri H.; Ikeda M.

    Oxidation-Responsive Supramolecular Hydrogel Based on a Simple Fmoc-Cysteine Derivative Capable of Showing Autonomous Gel–Sol–Gel Transitions

    Advanced Functional Materials

    https://doi.org/10.1002/adfm.202312999

     

  • dos Santos-Donado P.R.; Donado-Pestana C.M.; Rondán-Sanabria G.G.; Pauletti B.A.; Kawahara R.; Palmisano G.; Finardi-Filho F.

    Two-dimensional gel and shotgun proteomics approaches for the comparative evaluation of genetically modified maize

    Journal of Food Measurement and Characterization

    https://doi.org/10.1007/s11694-024-02397-x

     

     

     

  • Wang T.; Sobue A.; Watanabe S.; Komine O.; Saido T.C.; Saito T.; Yamanaka K.

    Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease

    Journal of Neuroinflammation

    https://doi.org/10.1186/s12974-024-03046-2

     

     

     

  • Marsh D.T.; Sugiyama A.; Imai Y.; Kato R.; Smid S.D.

    The structurally diverse phytocannabinoids cannabichromene, cannabigerol and cannabinol significantly inhibit amyloid β-evoked neurotoxicity and changes in cell morphology in PC12 cells

    Basic and Clinical Pharmacology and Toxicology

    https://doi.org/10.1111/bcpt.13943

     

  • Iijima H.; Zhang F.; Ambrosio F.; Matsui Y.

    Network-based cytokine inference implicates Oncostatin M as a driver of an inflammation phenotype in knee osteoarthritis

    Aging Cell

    https://doi.org/10.1111/acel.14043

     

  • Houlahan C.B.; Kong Y.; Johnston B.; Cielesh M.; Chau T.H.; Fenwick J.; Coleman P.R.; Hao H.; Haltiwanger R.S.; Thaysen-Andersen M.; Passam F.H.; Larance M.

    Analysis of the Healthy Platelet Proteome Identifies a New Form of Domain-Specific O-Fucosylation

    Molecular & cellular proteomics : MCP

    https://doi.org/10.1016/j.mcpro.2024.100717

     

     

  • Melo-Braga M.N.; Carvalho M.B.; Ferreira M.C.E.; Lavinder J.; Abbasi A.; Palmisano G.; Thaysen-Andersen M.; Sajadi M.M.; Ippolito G.C.; Felicori L.F.

    Unveiling the multifaceted landscape of N-glycosylation in antibody variable domains: Insights and implications

    International Journal of Biological Macromolecules

    https://doi.org/10.1016/j.ijbiomac.2023.128362

  • Hatanaka R.; Hane M.; Hayakawa K.; Morishita S.; Ohno S.; Yamaguchi Y.; Wu D.; Kitajima K.; Sato C.

    Identification of a buried β-strand as a novel disease-related motif in the human polysialyltransferases

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2023.105564

     

  • Kawade N.; Yamanaka K.

    Novel insights into brain lipid metabolism in Alzheimer’s disease: Oligodendrocytes and white matter abnormalities

    FEBS Open Bio

    https://doi.org/10.1002/2211-5463.13661

  • Enokido T.; Horie M.; Yoshino S.; Suzuki H.I.; Matsuki R.; Brunnstrom H.; Micke P.; Nagase T.; Saito A.; Miyashita N.

    Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma

    Molecular Cancer Research

    https://doi.org/10.1158/1541-7786.MCR-23-0229

     

  • Chernykh A.; Abrahams J.L.; Grant O.C.; Kambanis L.; Sumer-Bayraktar Z.; Ugonotti J.; Kawahara R.; Corcilius L.; Payne R.J.; Woods R.J.; Thaysen-Andersen M.

    Position-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase–mediated proteolysis of corticosteroid-binding globulin

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2023.105519

  • Hane M.

    Direct Observation Method for Glycans at Single-Molecule Level

    Trends in Glycoscience and Glycotechnology

    https://doi.org/10.4052/tigg.2341.6E

  • Kemmoku H.; Takahashi K.; Mukai K.; Mori T.; Hirosawa K.M.; Kiku F.; Uchida Y.; Kuchitsu Y.; Nishioka Y.; Sawa M.; Kishimoto T.; Tanaka K.; Yokota Y.; Arai H.; Suzuki K.G.N.; Taguchi T.

    Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol

    Nature Communications

    https://doi.org/10.1038/s41467-023-44317-5

     

  • Arafuka S.; Fujishiro H.; Torii Y.; Sekiguchi H.; Habuchi C.; Miwa A.; Yoshida M.; Iritani S.; Iwasaki Y.; Ikeda M.; Ozaki N.

    Neuropathological substrate of incident dementia in older patients with schizophrenia: A clinicopathological study

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13597

  • Sugiura S.; Shintani Y.; Higashi S.L.; Shibata A.; Ikeda M.

    Dihydrolevoglucosenone (Cyrene) as a Biobased Green Alternative to Organic Solvents for the Preparation of Supramolecular Gels Consisting of Self-Assembling Dipeptide Derivatives

    ACS Sustainable Chemistry and Engineering

    https://doi.org/10.1021/acssuschemeng.3c05026

     

  • Ando H.; Komura N.

    Recent progress in the synthesis of glycosphingolipids

    Current Opinion in Chemical Biology

    https://doi.org/10.1016/j.cbpa.2023.102423

     

  • Koike R.; Ota M.

    Elastic network model reveals distinct flexibilities of capping proteins bound to CARMIL and twinfilin-tail

    Proteins: Structure, Function and Bioinformatics

    https://doi.org/10.1002/prot.26560

     

  • Sawamura T.; Yuki N.; Aoki K.; Horii K.; Horii Y.; Naitou K.; Tsukamoto S.; Shiina T.; Shimizu Y.

    Alterations in descending brain-spinal pathways regulating colorectal motility in a rat model of Parkinson’s disease

    American journal of physiology. Gastrointestinal and liver physiology

    https://doi.org/10.1152/ajpgi.00181.2023

     

  • Yanaka S.; Watanabe H.; Yogo R.; Kongsema M.; Kondo S.; Yagi H.; Uchihashi T.; Kato K.

    Quantitative Analysis of Therapeutic Antibody Interactions with Fcγ Receptors Using High-Speed Atomic Force Microscopy

    Biological & pharmaceutical bulletin

    https://doi.org/10.1248/bpb.b23-00751

     

  • Tsagakis I.; Yamanaka K.

    An open chat with… Koji Yamanaka

    FEBS Open Bio

    https://doi.org/10.1002/2211-5463.13763

     

     

     

     

     

  • Pal R.; Yamazaki A.; Komura N.; Tanaka H.-N.; Imamura A.; Ishida H.; Ando H.

    Convergent synthesis of functionalized derivatives of stage-specific embryonic antigens 3 & 4

    Carbohydrate Research

    https://doi.org/10.1016/j.carres.2023.108990

     

  • Komine O.; Ohnuma S.; Hinohara K.; Hara Y.; Shimada M.; Akashi T.; Watanabe S.; Sobue A.; Kawade N.; Ogi T.; Yamanaka K.

    Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice

    iScience

    https://doi.org/10.1016/j.isci.2024.108872

     

  • Iwamoto S.; Kobayashi T.; Hanamatsu H.; Yokota I.; Teranishi Y.; Iwamoto A.; Kitagawa M.; Ashida S.; Sakurai A.; Matsuo S.; Myokan Y.; Sugimoto A.; Ushioda R.; Nagata K.; Gotoh N.; Nakajima K.; Nishikaze T.; Furukawa J.-I.; Itano N.

    Tolerable glycometabolic stress boosts cancer cell resilience through altered N-glycosylation and Notch signaling activation

    Cell Death and Disease

    https://doi.org/10.1038/s41419-024-06432-z

  • Sakai A.; Shinkuma S.; Miura N.; Deguchi T.; Oginezawa M.; Nakajima M.; Katsumi T.; Hayashi R.; Abe R.

    Possible relation of cathepsin C activity and seasonal fluctuation of skin lesions in Papillon Lefèvre syndrome

    British Journal of Dermatology

    https://doi.org/10.1093/bjd/ljad373

2023年

  • Fujiwara T.K.; Takeuchi S.; Kalay Z.; Nagai Y.; Tsunoyama T.A.; Kalkbrenner T.; Iwasawa K.; Ritchie K.P.; Suzuki K.G.N.; Kusumi A.

    Development of ultrafast camera-based single fluorescent-molecule imaging for cell biology

    Journal of Cell Biology

    https://doi.org/10.1083/jcb.202110160

  • Kobayashi J.; Wen R.; Nishikawa T.; Nunomura Y.; Suzuki T.; Sejima Y.; Gokan T.; Furukawa M.; Yokota T.; Osawa N.; Sato Y.; Nibu Y.; Mizutani T.; Oba M.

    Natto extract inhibits infection caused by the Aujeszky’s disease virus in mice

    Microbiology and Immunology

    https://doi.org/10.1111/1348-0421.13099

  • Ta H.P.; Clarisse C.; Maes E.; Yamakawa N.; Guérardel Y.; Krzewinski F.; Zarzycka W.; Touboul D.; Girardeau A.; Fonseca F.; Kermarrec A.; Viau M.; Riaublanc A.; Ropers M.H.

    Membrane lipid composition of Carnobacterium maltaromaticum CNCM I-3298, a highly cryoresistant lactic bacterium

    Chemistry and Physics of Lipids

    https://doi.org/10.1016/j.chemphyslip.2023.105326

     

  • Lo T.; Kushima I.; Kimura H.; Aleksic B.; Okada T.; Kato H.; Inada T.; Nawa Y.; Torii Y.; Yamamoto M.; Kimura R.; Funabiki Y.; Kosaka H.; Numata S.; Kasai K.; Sasaki T.; Yokoyama S.; Munesue T.; Hashimoto R.; Yasuda Y.; Fujimoto M.; Usami M.; Itokawa M.; Arai M.; Ohi K.; Someya T.; Watanabe Y.; Egawa J.; Takahashi T.; Suzuki M.; Yamasue H.; Iwata N.; Ikeda M.; Ozaki N.

    Association between copy number variations in parkin (PRKN) and schizophrenia and autism spectrum disorder: A case–control study

    Neuropsychopharmacology Reports

    https://doi.org/10.1002/npr2.12370

  • Watanabe S.; Murata Y.; Oka Y.; Oiwa K.; Horiuchi M.; Iguchi Y.; Komine O.; Sobue A.; Katsuno M.; Ogi T.; Yamanaka K.

    Mitochondria-associated membrane collapse impairs TBK1-mediated proteostatic stress response in ALS

    Proceedings of the National Academy of Sciences of the United States of America

    https://doi.org/10.1073/pnas.2315347120

  • Senju C.; Nakazawa Y.; Oso T.; Shimada M.; Kato K.; Matsuse M.; Tsujimoto M.; Masaki T.; Miyazaki Y.; Fukushima S.; Tateishi S.; Utani A.; Murota H.; Tanaka K.; Mitsutake N.; Moriwaki S.; Nishigori C.; Ogi T.

    Deep intronic founder mutations identified in the ERCC4/XPF gene are potential therapeutic targets for a high-frequency form of xeroderma pigmentosum

    Proceedings of the National Academy of Sciences of the United States of America

    https://doi.org/10.1073/pnas.2217423120

  • Hayakawa K.; Hane M.; Hamagami H.; Imai M.; Tanaka H.; Kitajima K.; Sato C.

    Interactions between polysialic acid and dopamine-lead compounds as revealed by biochemical and in silico docking simulation analyses

    Glycoconjugate Journal

    https://doi.org/10.1007/s10719-023-10119-6

  • Hagino R.; Mozaki K.; Komura N.; Imamura A.; Ishida H.; Ando H.; Tanaka H.-N.

    Synthetic Approaches to Ribosyl Adenosine 5′,5′′-Diphosphate Fragment of Poly(ADP-ribose)

    European Journal of Organic Chemistry

    https://doi.org/10.1002/ejoc.202300875

  • Ohkawa Y.; Kanto N.; Nakano M.; Fujinawa R.; Kizuka Y.; Johnson E.L.; Harada Y.; Tamura J.-I.; Taniguchi N.

    Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2023.105052

  • Irie K.; Oda Y.; Sumikama T.; Oshima A.; Fujiyoshi Y.

    The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel

    Nature Communications

    https://doi.org/10.1038/s41467-023-39987-0

  • Arafuka S.; Fujishiro H.; Torii Y.; Sekiguchi H.; Habuchi C.; Miwa A.; Yoshida M.; Iritani S.; Iwasaki Y.; Ikeda M.; Ozaki N.

    Neuropathological substrate of incident dementia in older patients with schizophrenia: A clinicopathological study

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13597

  • Kato D.; Aoyama Y.; Nishida K.; Takahashi Y.; Sakamoto T.; Takeda I.; Tatematsu T.; Go S.; Saito Y.; Kunishima S.; Cheng J.; Hou L.; Tachibana Y.; Sugio S.; Kondo R.; Eto F.; Sato S.; Moorhouse A.J.; Yao I.; Kadomatsu K.; Setou M.; Wake H.

    Regulation of lipid synthesis in myelin modulates neural activity and is required for motor learning

    GLIA

    https://doi.org/10.1002/glia.24441

  • Murao M.; Kato R.; Kusano S.; Hisamatsu R.; Endo H.; Kawabata Y.; Kimura S.; Sato A.; Mori H.; Itami K.; Torii K.U.; Hagihara S.; Uchida N.

    A Small Compound, HYGIC, Promotes Hypocotyl Growth Through Ectopic Ethylene Response

    Plant and Cell Physiology

    https://doi.org/10.1093/pcp/pcad083

  • Carnielli C.M.; de Lima Morais T.M.; de Sá Patroni F.M.; Ribeiro A.C.P.; Brandão T.B.; Sobroza E.; Matos L.L.; Kowalski L.P.; Leme A.F.P.; Kawahara R.; Thaysen-Andersen M.

    Comprehensive Glycoprofiling of Oral Tumors Associates N-Glycosylation With Lymph Node Metastasis and Patient Survival

    Molecular and Cellular Proteomics

    https://doi.org/10.1016/j.mcpro.2023.100586

  • Furukawa S.; Kushima I.; Aleksic B.; Ozaki N.

    Case reports of two siblings with autism spectrum disorder and 15q13.3 deletions

    Neuropsychopharmacology Reports

    https://doi.org/10.1002/npr2.12340

  • Jilani N.A.K.; Oka N.; Ando K.; Hasbullah S.A.

    Synthesis, Characterisation and Binding Evaluation of New 6-Amidinoindole Compound as the Potential Heme Binder; [Sintesis, Pencirian dan Penilaian Pengikatan Sebatian 6-Amidinoindol Baharu sebagai Pengikat Heme Berpotensi]

    Sains Malaysiana

    https://doi.org/10.17576/jsm-2023-5204-15

  • Ohkawa Y.; Kitano M.; Maeda K.; Nakano M.; Kanto N.; Kizuka Y.; Seike M.; Azuma A.; Yamaguchi Y.; Ookawara T.; Miyoshi E.; Taniguchi N.

    Core Fucosylation Is Required for the Secretion of and the Enzymatic Activity of SOD3 in Nonsmall-Cell Lung Cancer Cells

    Antioxidants and Redox Signaling

    https://doi.org/10.1089/ars.2022.0010

  • Farshadyeganeh P.; Nazim M.; Zhang R.; Ohkawara B.; Nakajima K.; Rahman M.A.; Nasrin F.; Ito M.; Takeda J.-I.; Ohe K.; Miyasaka Y.; Ohno T.; Masuda A.; Ohno K.

    Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction

    iScience

    https://doi.org/10.1016/j.isci.2023.107746

  • Inagaki M., Abe N., Li Z., Nakashima Y., Acharyya S., Ogawa K., Kawaguchi D., Hiraoka H., Banno A., Meng Z., Tada M., Ishida T., Lyu P., Kokubo K., Murase H., Hashiya F., Kimura Y., Uchida S., Abe H.

    Cap analogs with a hydrophobic photocleavable tag enable facile purification of fully capped mRNA with various cap structures

    Nature Communications

    https://doi.org/10.1038/s41467-023-38244-8

  • Sobue A., Komine O., Yamanaka K.

    Neuroinflammation in Alzheimer’s disease: microglial signature and their relevance to disease

    Inflammation and Regeneration

    https://doi.org/10.1186/s41232-023-00277-3

  • Kimura H., Kishi S., Narita H., Tanaka T., Okada T., Fujisawa D., Sugita N., Noma S., Matsumoto Y., Ohashi A., Mitsuyasu H., Yoshida K., Kawasaki H., Nishimura K., Ogura Y., Ozaki N.

    Comorbid psychiatric disorders and long-term survival after liver transplantation in transplant facilities with a psychiatric consultation-liaison team: a multicenter retrospective study

    BMC Gastroenterology

    https://doi.org/10.1186/s12876-023-02735-1

  • Yamauchi K., Soyano M., Kobayashi M., Kamatari Y.O., Mitsunaga T.

    Protein aggregation model to explain the bioactivity of condensed tannins

    Food Chemistry

    https://doi.org/10.1016/j.foodchem.2023.135870

  • Suzuki K., Nishio N., Kimura H., Tokura T., Kishi S., Ozaki N., Fujimoto Y., Sone M.

    Comparison of quality of life and psychological distress in patients with tongue cancer undergoing a total/subtotal glossectomy or extended hemiglossectomy and free flap transfer: a prospective evaluation

    International Journal of Oral and Maxillofacial Surgery

    https://doi.org/10.1016/j.ijom.2022.11.010

  • Ikazaki T., Ishikawa E., Tamashima H., Akiyama H., Kimuro Y., Yoritate M., Matoba H., Imamura A., Ishida H., Yamasaki S., Hirai G.

    Ligand-Controlled Stereoselective Synthesis and Biological Activity of 2-Exomethylene Pseudo-glycoconjugates: Discovery of Mincle-Selective Ligands

    Angewandte Chemie – International Edition

    https://doi.org/10.1002/anie.202302569

  • Kozai D., Numoto N., Nishikawa K., Kamegawa A., Kawasaki S., Hiroaki Y., Irie K., Oshima A., Hanzawa H., Shimada K., Kitano Y., Fujiyoshi Y.

    Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit: Recognition mechanism of mirogabalin for α2δ1

    Journal of Molecular Biology

    https://doi.org/10.1016/j.jmb.2023.168049

  • Nishiguchi S., Kasai R.S., Uchihashi T.

    Antiparallel dimer structure of CELSR cadherin in solution revealed by high-speed-atomic force microscopy

    Proceedings of the National Academy of Sciences of the United States of America

    https://doi.org/10.1073/pnas.2302047120

  • Asano T., Udagawa T., Komura N., Imamura A., Ishida H., Ando H., Tanaka H.-N.

    Unprecedented neighboring group participation of C2 N-imidoxy functionalities for 1,2-trans-selective glycosylation

    Carbohydrate Research

    https://doi.org/10.1016/j.carres.2023.108808

  • Kusumi A., Tsunoyama T.A., Tang B., Hirosawa K.M., Morone N., Fujiwara T.K., Suzuki K.G.N.

    Cholesterol- and actin-centered view of the plasma membrane: updating the Singer-Nicolson fluid mosaic model to commemorate its 50th anniversary

    Molecular biology of the cell

    https://doi.org/10.1091/mbc.E20-12-0809

  • Sugiura K., Kawai Y., Yamamoto A., Yoshioka H., Kiyohara Y., Iida A., Ozawa Y., Nishikawa M., Miura N., Hanamatsu H., Furukawa J.-I., Shinohara Y.

    Exposure to brefeldin A induces unusual expression of hybrid- and complex-type free N-glycans in HepG2 cells

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2023.130331

  • Liu Y.-S., Wang Y., Zhou X., Zhang L., Yang G., Gao X.-D., Murakami Y., Fujita M., Kinoshita T.

    Accumulated precursors of specific GPI-anchored proteins upregulate GPI biosynthesis with ARV1

    The Journal of cell biology

    https://doi.org/10.1083/jcb.202208159

  • Kondo Y., Okajima T.

    Inhibitory machinery for the functional dystroglycan glycosylation

    Journal of biochemistry

    https://doi.org/10.1093/jb/mvad003

  • Minami S., Niwa T., Uemura E., Koike R., Taguchi H., Ota M.

    Prediction of chaperonin GroE substrates using small structural patterns of proteins

    FEBS Open Bio

    https://doi.org/10.1002/2211-5463.13590

  • Hanamatsu H., Miura Y., Nishikaze T., Yokota I., Homan K., Onodera T., Hayakawa Y., Iwasaki N., Furukawa J.-I.

    Simultaneous and sialic acid linkage-specific N- and O-linked glycan analysis by ester-to-amide derivatization

    Glycoconjugate Journal

    https://doi.org/10.1007/s10719-023-10109-8

  • Chau T.H., Chernykh A., Kawahara R., Thaysen-Andersen M.

    Critical considerations in N-glycoproteomics

    Current Opinion in Chemical Biology

    https://doi.org/10.1016/j.cbpa.2023.102272

  • Watanabe S., Horiuchi M., Murata Y., Komine O., Kawade N., Sobue A., Yamanaka K.

    Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis

    Neurobiology of Disease

    https://doi.org/10.1016/j.nbd.2023.106031

  • Nakajo T., Kusaka S., Hiraoka H., Nomura K., Matsubara N., Baba R., Yoshida Y., Nakamoto K., Honma M., Iguchi H., Uchihashi T., Abe H., Matsuda R.

    Creation of single molecular conjugates of metal-organic cages and DNA

    Chemical Communications

    https://doi.org/10.1039/d3cc00460k

  • Kato H., Kimura H., Kushima I., Takahashi N., Aleksic B., Ozaki N.

    The genetic architecture of schizophrenia: review of large-scale genetic studies

    Journal of Human Genetics

    https://doi.org/10.1038/s10038-022-01059-4

  • Sorin M.N., Di Maio A., Silva L.M., Ebert D., Delannoy C.P., Nguyen N.-K., Guerardel Y., Chai W., Halary F., Renaudin-Autain K., Liu Y., Bressollette-Bodin C., Stehle T., McIlroy D.

    Structural and functional analysis of natural capsid variants suggests sialic acid-independent entry of BK polyomavirus

    Cell Reports

    https://doi.org/10.1016/j.celrep.2023.112114

  • Soon J.W., Oohora K., Uchihashi T., Hayashi T.

    Disulfide Bond-mediated Oligomerization of a Green Fluorescent Protein in Solution

    Chemistry Letters

    https://doi.org/10.1246/cl.220495

  • Rahman M.M., Nakanishi R., Tsukada F., Takashima S., Wakihara Y., Kamatari Y.O., Shimizu K., Okada A., Inoshima Y.

    Identification of Suitable Internal Control miRNAs in Bovine Milk Small Extracellular Vesicles for Normalization in Quantitative Real-Time Polymerase Chain Reaction

    Membranes

    https://doi.org/10.3390/membranes13020185

  • Anbo H., Sakuma K., Fukuchi S., Ota M.

    How AlphaFold2 Predicts Conditionally Folding Regions Annotated in an Intrinsically Disordered Protein Database, IDEAL

    Biology

    https://doi.org/10.3390/biology12020182

  • Saitoh S., Takaki T., Nakajima K., Wo B., Terashima H., Shimo S., Nguyen H.B., Thai T.Q., Kumamoto K., Kunisawa K., Nagao S., Tojo A., Ohno N., Takahashi K.

    Treatment of tubular damage in high-fat-diet-fed obese mice using sodium-glucose cotransporter inhibitors

    PLoS ONE

    https://doi.org/10.1371/journal.pone.0281770

  • Suzuki K.G.N., Kusumi A.

    Refinement of Singer-Nicolson fluid-mosaic model by microscopy imaging: Lipid rafts and actin-induced membrane compartmentalization

    Biochimica et Biophysica Acta – Biomembranes

    https://di.org/10.1016/j.bbamem.2022.184093

  • Abe J., Takeda Y., Kikuma T., Kizuka Y., Kajiura H., Kajihara Y., Ito Y.

    Squaryl group-modified UDP analogs as inhibitors of the endoplasmic reticulum-resident folding sensor enzyme UGGT

    Chemical Communications

    https://doi.org/10.1039/d2cc06634c

  • Nakagawa T., Iwaki Y., Wu D., Hane M., Sato C., Kitajima K.

    Identification and characterization of a deaminoneuraminic acid (Kdn)-specific aldolase from Sphingobacterium species

    Glycobiology

    https://doi.org/10.1093/glycob/cwac053

  • Yamashita H., Komine O., Fujimori-Tonou N., Yamanaka K.

    Comprehensive expression analysis with cell-type-specific transcriptome in ALS-linked mutant SOD1 mice: Revisiting the active role of glial cells in disease

    Frontiers in Cellular Neuroscience

    https://doi.org/10.3389/fncel.2022.1045647

  • Hasegawa S., Inagaki M., Kato S., Li Z., Kimura Y., Abe H.

    Synthesis of nucleoside oligophosphates by electrophilic activation of phosphorothioate

    Organic and Biomolecular Chemistry

    https://doi.org/10.1039/d2ob02260e

  • Suzuki K.G.N., Komura N., Ando H.

    Recently developed glycosphingolipid probes and their dynamic behavior in cell plasma membranes as revealed by single-molecule imaging

    Glycoconjugate Journal

    https://doi.org/10.1007/s10719-023-10116-9

  • Kimura H., Kushima I., Banno M., Inada T., Yoshimi A., Aleksic B., Ozaki N.

    Clinical characterization of patients with schizophrenia and 16p13.11 duplication: A case series

    Neuropsychopharmacology Reports

    https://doi.org/10.1002/npr2.12334

  • Kawamata M., Suzuki H.I., Kimura R., Suzuki A.

    Optimization of Cas9 activity through the addition of cytosine extensions to single-guide RNAs

    Nature Biomedical Engineering

    https://doi.org/10.1038/s41551-023-01011-7

  • Arioka Y., Okumura H., Sakaguchi H., Ozaki N.

    Shedding light on latent pathogenesis and pathophysiology of mental disorders: the potential of iPS cell technology

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13545

  • Miyake N., Tsurusaki Y., Fukai R., Kushima I., Okamoto N., Ohashi K., Nakamura K., Hashimoto R., Hiraki Y., Son S., Kato M., Sakai Y., Osaka H., Deguchi K., Matsuishi T., Takeshita S., Fattal-Valevski A., Ekhilevitch N., Tohyama J., Yap P., Keng W.T., Kobayashi H., Takubo K., Okada T., Saitoh S., Yasuda Y., Murai T., Nakamura K., Ohga S., Matsumoto A., Inoue K., Saikusa T., Hershkovitz T., Kobayashi Y., Morikawa M., Ito A., Hara T., Uno Y., Seiwa C., Ishizuka K., Shirahata E., Fujita A., Koshimizu E., Miyatake S., Takata A., Mizuguchi T., Ozaki N., Matsumoto N.

    Molecular diagnosis of 405 individuals with autism spectrum disorder

    European Journal of Human Genetics

    https://doi.org/10.1038/s41431-023-01335-7

  • Yamanaka K.

    Neuroinflammation in neurodegenerative disease

    Nagoya Journal of Medical Science

    https://doi.org/10.18999/nagjms.85.1.30

  • Maekawa K., Yamanaka K.

    Role of sex hormones in neuroinflammation in Alzheimer’s disease

    Clinical and Experimental Neuroimmunology

    https://doi.org/10.1111/cen3.12744

  • Chau T.H., Chernykh A., Ugonotti J., Parker B.L., Kawahara R., Thaysen-Andersen M.

    Glycomics-Assisted Glycoproteomics Enables Deep and Unbiased N-Glycoproteome Profiling of Complex Biological Specimens

    Methods in molecular biology (Clifton, N.J.)

    https://doi.org/10.1007/978-1-0716-2978-9_16

  • Uegaki R., Uchino H., Wasada H., Suga H.

    Fumonisin reduction using fungicides in forage corn cultivation

    Grassland Science

    https://doi.org/10.1111/grs.12397

  • Wakayama K., Kimura S., Kobatake Y., Kamishina H., Nishii N., Takashima S., Honda R., Kamatari Y.O.

    Molecular Mechanisms of Aggregation of Canine SOD1 E40K Amyloidogenic Mutant Protein

    Molecules

    https://doi.org/10.3390/molecules28010156

  • Hamajima S., Komura N., Tanaka H.-N., Imamura A., Ishida H., Ichiyanagi T., Ando H.

    Investigation of the Protection of the C4 Hydroxyl Group in Macrobicyclic Kdo Donors

    Molecules

    https://doi.org/10.3390/molecules28010102

  • Lo T., Kushima I., Aleksic B., Yoshimi A., Someya T., Watanabe Y., Ozaki N.

    Clinical manifestations of schizophrenia in four patients with variants in voltage-gated calcium channel-encoding genes: a case series

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13494

  • Matsuo Y., Uchihashi T., Inada T.

    Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex

    Nature Communications

    https://doi.org/10.1038/s41467-022-35608-4

  • Omoto T., Wu D., Maruyama E., Tajima K., Hane M., Sato C., Kitajima K.

    Forced expression of α2,3-sialyltransferase IV rescues impaired heart development in α2,6-sialyltransferase I-deficient medaka

    Biochemical and Biophysical Research Communications

    https://doi.org/10.1016/j.bbrc.2023.01.010

  • Yokoyama S., Hayashi M., Goto T., Muto Y., Tanaka K.

    Identification of cfxA gene variants and susceptibility patterns in β-lactamase-producing Prevotella strains

    Anaerobe

    https://doi.org/10.1016/j.anaerobe.2022.102688

  • Okawa R., Hayashi Y., Yamashita Y., Matsubayashi Y., Ogawa-Ohnishi M.

    Arabinogalactan protein polysaccharide chains are required for normal biogenesis of plasmodesmata

    Plant Journal

    https://doi.org/10.1111/tpj.16061

  • Hayasaka R., Tabata S., Hasebe M., Ikeda S., Hikita T., Oneyama C., Yoshitake J., Onoshima D., Takahashi K., Shibata T., Uchida K., Baba Y., Soga T., Tomita M., Hirayama A.

    Metabolomics of small extracellular vesicles derived from isocitrate dehydrogenase 1-mutant HCT116 cells collected by semi-automated size exclusion chromatography

    Frontiers in Molecular Biosciences

    https://doi.org/10.3389/fmolb.2022.1049402

  • Yamashita H., Komine O., Fujimori-Tonou N., Yamanaka K.

    Comprehensive expression analysis with cell-type-specific transcriptome in ALS-linked mutant SOD1 mice: Revisiting the active role of glial cells in disease

    Frontiers in Cellular Neuroscience

    https://doi.org/10.3389/fncel.2022.1045647

     

  • Nakagawa Y.

    Recent Progress in the Development and Application of Lectin Mimics

    Trends in Glycoscience and Glycotechnology

    https://doi.org/10.4052/tigg.2207.1E

  • Hane M.

    Sialoglycomic Analysis Using Sialic Acid Recognition Molecules as Probes

    Trends in Glycoscience and Glycotechnology

    https://doi.org/10.4052/tigg.2225.6E

  • Sugiyama Y., Uno K., Matsui Y.

    Types of anomalies in two-dimensional videobased gait analysis in uncontrolled environments

    PLoS Computational Biology

    https://doi.org/10.1371/journal.pcbi.1009989

  • Suganuma Y., Imamura A., Ando H., Kiso M., Takematsu H., Tsubata T., Ishida H.

    Improved synthesis of CD22-binding sialosides and its application for further development of potent CD22 inhibitors

    Glycoconjugate Journal

    https://doi.org/10.1007/s10719-023-10098-8

  • Yamaguchi E., Komura N., Tanaka H.-N., Imamura A., Ishida H., Groux-Degroote S., Mühlenhoff M., Suzuki K.G.N., Ando H.

    Fluorescent GD2 analog for single-molecule imaging

    Glycoconjugate Journal

    https://doi.org/10.1007/s10719-023-10102-1

  • Fu B., Wu D., Yasumasu S., Hane M., Sato C., Kitajima K.

    Critical Role of the Cortical Alveolus Protease Alveolin in Chorion Hardening In Vivo at Medaka Fertilization

    Biomolecules

    https://doi.org/10.3390/biom13010146

  • Komatsu S., Kitai H., Suzuki H.I.

    Network Regulation of microRNA Biogenesis and Target Interaction

    Cells

    https://doi.org/10.3390/cells12020306

  • Imamura A., Ando H., Ishida H.

    Chemical Synthesis of Gangliosides

    Methods in Molecular Biology

    https://doi.org/10.1007/978-1-0716-2910-9_8

  • Hanamatsu H., Nishikaze T., Furukawa J.-I.

    Comprehensive Glycan Analysis of Sphingolipids in Human Serum/Plasma

    Methods in Molecular Biology

    https://doi.org/10.1007/978-1-0716-2910-9_21

  • Suzuki K.G.N.

    Single-Molecule Imaging of Ganglioside Probes in Living Cell Plasma Membranes

    Methods in Molecular Biology

    https://doi.org/10.1007/978-1-0716-2910-9_17

  • Hanamatsu H., Makino S., Ohara M., Suda G., Yokota I., Nishihara S., Sakamoto N., Furukawa J.-I.

    Simultaneous determination of heparan sulfate, chondroitin/dermatan sulfates, and hyaluronan glycosaminoglycan disaccharides by high-performance liquid chromatography using a reverse-phase column with adamantyl groups

    Journal of Chromatography A

    https://doi.org/10.1016/j.chroma.2022.463748

  • Hirata T., Harada Y., Hirosawa K.M., Tokoro Y., Suzuki K.G.N., Kizuka Y.

    N-acetylglucosaminyltransferase-V (GnT-V)-enriched small extracellular vesicles mediate N-glycan remodeling in recipient cells

    iScience

    https://doi.org/10.1016/j.isci.2022.105747

  • Suzuki K.G.N., Kusumi A.

    Refinement of Singer-Nicolson fluid-mosaic model by microscopy imaging: Lipid rafts and actin-induced membrane compartmentalization

    Biochimica et Biophysica Acta – Biomembranes

    https://doi.org/10.1016/j.bbamem.2022.184093

  • Ren W.-W., Fujita M.

    Simple N-Glycan Profile Analysis Using Lectin Staining, Mass Spectrometry, and GlycoMaple

    Methods in Molecular Biology

    https://doi.org/10.1007/978-1-0716-2639-9_41

  • Li F., Ebihara A., Sakahara Y., Matsumoto S., Ueno R., Bao W., Kimura M., Fuji S.-I., Shimizu M., Kageyama K., Suga H.

    Synergistic effect of amino acid substitutions in CYP51B for prochloraz resistance in Fusarium fujikuroi

    Pesticide Biochemistry and Physiology

    https://doi.org/10.1016/j.pestbp.2022.105291

  • Inokuchi J.-I., Go S., Hirabayashi Y.

    Synthesis of O-Linked Glycoconjugates in the Nervous System

    Advances in Neurobiology

    https://doi.org/10.1007/978-3-031-12390-0_4

2022年

  • Yasuda T., Watanabe H., Hirosawa K.M., Suzuki K.G.N., Suga K., Hanashima S.

    Fluorescence Spectroscopic Analysis of Lateral and Transbilayer Fluidity of Exosome Membranes

    Langmuir

    https://doi.org/10.1021/acs.langmuir.2c02258

     

  • Hamajima S., Komura N., Tanaka H.-N., Imamura A., Ishida H., Noguchi H., Ichiyanagi T., Ando H.

    Full Stereocontrol in α-Glycosidation of 3-Deoxy- d – Manno-2-octulosonic Acid (Kdo) Using Macrobicyclic Glycosyl Donors

    Organic Letters

    https://doi.org/10.1021/acs.orglett.2c03542

  • Tomida S., Nagae M., Kizuka Y.

    The stem region of α1,6-fucosyltransferase FUT8 is required for multimer formation but not catalytic activity

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2022.102676

  • Kitai H., Kato N., Ogami K., Komatsu S., Watanabe Y., Yoshino S., Koshi E., Tsubota S., Funahashi Y., Maeda T., Furuhashi K., Ishimoto T., Kosugi T., Maruyama S., Kadomatsu K., Suzuki H.I.

    Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis

    BMC Biology

    https://doi.org/10.1186/s12915-022-01447-4

  • Suzuki K., Tange M., Yamagishi R., Hanada H., Mukai S., Sato T., Tanaka T., Akashi T., Kadomatsu K., Maeda T., Miida T., Takeuchi I., Murakami H., Sekido Y., Murakami-Tonami Y.

    SMG6 regulates DNA damage and cell survival in Hippo pathway kinase LATS2-inactivated malignant mesothelioma

    Cell Death Discovery

    https://doi.org/10.1038/s41420-022-01232-w

  • Mizobuchi K., Kushima I., Kato H., Miyajima M., Kimura H., Ozaki N.

    Turner syndrome presenting with idiopathic regression: A case report

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13483

  • Chantarasrivong C., Okada R., Yamane Y., Yang X., Higuchi Y., Konishi M., Komura N., Ando H., Yokokawa R., Yamashita F.

    Disposition of E-selectin-targeting liposomes in tumor spheroids with a perfusable vascular network

    Drug Metabolism and Pharmacokinetics

    https://doi.org/10.1016/j.dmpk.2022.100469

  • Kushima I., Aleksic B., Kimura H., Nakatochi M., Lo T., Ikeda M., Arai M., Hashimoto R., Numata S., Okamura Y., Obara T., Inada T., Ozaki N.

    X chromosome aneuploidies and schizophrenia: association analysis and phenotypic characterization

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13474

  • Kawashima N., Naito S., Hanamatsu H., Nagane M., Takeuchi Y., Furukawa J.-I., Iwasaki N., Yamashita T., Nakayama K.-I.

    Glycosphingolipid GM3 prevents albuminuria and podocytopathy induced by anti-nephrin antibody

    Scientific Reports

    https://doi.org/10.1038/s41598-022-20265-w

  • Young V.C., Nakanishi H., Meyer D.J., Nishizawa T., Oshima A., Artigas P., Abe K.

    Structure and function of H+/K+ pump mutants reveal Na+/K+ pump mechanisms

    Nature Communications

    https://doi.org/10.1038/s41467-022-32793-0

  • Kizuka Y.

    Metabolic utilization and remodeling of glycan biosynthesis using fucose analogs

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2022.130243

  • Yang Y., Liu G., Li F., Carey L.B., Sun C., Ling K., Tachikawa H., Fujita M., Gao X.-D., Nakanishi H.

    Receptor for advanced glycation end-products (RAGE) mediates phagocytosis in nonprofessional phagocytes

    Communications Biology

    https://doi.org/1038.42003/s022-03791-1

  • Shimamura Y., Furuhashi K., Tanaka A., Karasawa M., Nozaki T., Komatsu S., Watanabe K., Shimizu A., Minatoguchi S., Matsuyama M., Sawa Y., Tsuboi N., Ishimoto T., Suzuki H.I., Maruyama S.

    Mesenchymal stem cells exert renoprotection via extracellular vesicle-mediated modulation of M2 macrophages and spleen-kidney network

    Communications Biology

    https://doi.org/1038.42003/s022-03712-2

  • Ertunc N., Phitak T., Wu D., Fujita H., Hane M., Sato C., Kitajima K.

    Sulfation of sialic acid is ubiquitous and essential for vertebrate development

    Scientific Reports

    https://doi.org/1038.41598/s022-15143-4

  • Nagae M., Hirata T., Tateno H., Mishra S.K., Manabe N., Osada N., Tokoro Y., Yamaguchi Y., Doerksen R.J., Shimizu T., Kizuka Y.

    Discovery of a lectin domain that regulates enzyme activity in mouse N-acetylglucosaminyltransferase-IVa (MGAT4A)

    Communications Biology

    https://doi.org/1038.42003/s022-03661-w

  • Suzuki S., Iida M., Hiroaki Y., Tanaka K., Kawamoto A., Kato T., Oshima A.

    Structural insight into the activation mechanism of MrgD with heterotrimeric Gi-protein revealed by cryo-EM

    Communications Biology

    https://doi.org/1038.42003/s022-03668-3

  • Kimura H., Nakatochi M., Aleksic B., Guevara J., Toyama M., Hayashi Y., Kato H., Kushima I., Morikawa M., Ishizuka K., Okada T., Tsurusaki Y., Fujita A., Miyake N., Ogi T., Takata A., Matsumoto N., Buxbaum J., Ozaki N., Sebat J.

    Exome sequencing analysis of Japanese autism spectrum disorder case-control sample supports an increased burden of synaptic function-related genes

    Translational Psychiatry

    https://doi.org/1038.41398/s022-02033-6

  • Imai Y., Iida M., Kanie K., Katsuno M., Kato R.

    Label-free morphological sub-population cytometry for sensitive phenotypic screening of heterogenous neural disease model cells

    Scientific Reports

    https://doi.org/1038.41598/s022-12250-0

  • Huang S., Haga Y., Li J., Zhang J., Kweon H.K., Seino J., Hirayama H., Fujita M., Moremen K.W., Andrews P., Suzuki T., Wang Y.

    Mitotic phosphorylation inhibits the Golgi mannosidase MAN1A1

    Cell Reports

    https://doi.org/10.1016/j.celrep.2022.111679

  • Ohyama Y., Yamaguchi H., Ogata S., Chiurlia S., Cox S.N., Kouri N.-M., Stangou M.J., Nakajima K., Hayashi H., Inaguma D., Hasegawa M., Yuzawa Y., Tsuboi N., Renfrow M.B., Novak J., Papagianni A.A., Schena F.P., Takahashi K.

    Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy

    iScience

    https://doi.org/10.1016/j.isci.2022.105223

  • Kondoh K., Akahori H., Muto Y., Terada T.

    Identification of Key Genes and Pathways Associated with Preeclampsia by a WGCNA and an Evolutionary Approach

    Genes

    https://doi.org/10.3390/genes13112134

  • Nagao H., Ninomiya M., Sugiyama H., Itabashi A., Uno K., Tanaka K., Koketsu M.

    Comparative analysis of p-terphenylquinone and seriniquinone derivatives as reactive oxygen species-modulating agents

    Bioorganic and Medicinal Chemistry Letters

    https://doi.org/10.1016/j.bmcl.2022.128992

  • Tsutsumi N., Ito A., Niko Y., Bando Y., Takahashi K., Ikeda M., Yoneyama K., Nakamura T., Izumi M., Ochi R.

    Glycolipid-Type Amphiphiles with a Small Anilinochloromaleimide-Based Luminogen Exhibiting Aggregation-Induced Emission

    ChemistrySelect

    https://doi.org/10.1002/slct.202202559

  • Chan F.-Y., Kurosaki R., Ganser C., Takeda T., Uchihashi T.

    Tip-scan high-speed atomic force microscopy with a uniaxial substrate stretching device for studying dynamics of biomolecules under mechanical stress

    Review of Scientific Instruments

    https://doi.org/10.1063/5.0111017

  • Miura N., Hanamatsu H., Yokota I., Akasaka-Manya K., Manya H., Endo T., Shinohara Y., Furukawa J.-I.

    Toolbox Accelerating Glycomics (TAG): Improving Large-Scale Serum Glycomics and Refinement to Identify SALSA-Modified and Rare Glycans

    International Journal of Molecular Sciences

    https://doi.org/10.3390/ijms232113097

  • Zhang A., Tsukamoto Y., Takeuchi H., Nishiwaki K., Tashima Y., Okajima T.

    Secretory expression of mammalian NOTCH tandem epidermal growth factor-like repeats based on increased O-glycosylation

    Analytical Biochemistry

    https://doi.org/10.1016/j.ab.2022.114881

  • Miyakawa K., Miyashita N., Horie M., Terasaki Y., Tanaka H., Urushiyama H., Fukuda K., Okabe Y., Ishii T., Kuwahara N., Suzuki H.I., Nagase T., Saito A.

    ASCL1 regulates super-enhancer-associated miRNAs to define molecular subtypes of small cell lung cancer

    Cancer Science

    https://doi.org/10.1111/cas.15481

  • Lyu F., An S., Kobayashi Y., Nomura K., Baba R., Abe N., Hiraoka H., Hashiya F., Shu Z., Ui-Tei K., Kimura Y., Abe H.

    A 2′-modified uridine analog, 2′-O-(methylthiomethoxy)methyl uridine, for siRNA applications

    Bioorganic and Medicinal Chemistry Letters

    https://doi.org/1016.2022/j.bmcl.128939

  • Yoshitake J., Azami M., Sei H., Onoshima D., Takahashi K., Hirayama A., Uchida K., Baba Y., Shibata T.

    Rapid Isolation of Extracellular Vesicles Using a Hydrophilic Porous Silica Gel-Based Size-Exclusion Chromatography Column

    Analytical Chemistry

    https://doi.org/10.1021/acs.analchem.2c01053

  • Suga H., Hayashi M., Kushiro M., Miyano N., Inoue H., Nakajima K., Kawakami T., Tonooka T., Nakajima T., Shimizu M., Kageyama K.

    A Novel Medium for Isolating Two Japanese Species in the Fusarium graminearum Species Complex and a Dipstick DNA Chromatography Assay for Species Identification and Trichothecene Typing

    Journal of Fungi

    https://doi.org/10.3390/jof8101048

  • Hirata T., Yang J., Tomida S., Tokoro Y., Kinoshita T., Fujita M., Kizuka Y.

    ER entry pathway and glycosylation of GPI-anchored proteins are determined by N-terminal signal sequence and C-terminal GPI-attachment sequence

    Journal of Biological Chemistry

    https://doi.org/1016.2022/j.jbc.102444

  • Yamamoto T., Yasuda S., Kasai R.S., Nakano R., Hikiri S., Sugaya K., Hayashi T., Ogasawara S., Shiroishi M., Fujiwara T.K., Kinoshita M., Murata T.

    A methodology for creating mutants of G-protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering

    Protein Science

    https://doi.org/10.1002/pro.4425

  • Murakami A., Noda S., Kazuta T., Hirano S., Kimura S., Nakanishi H., Matsuo K., Tsujikawa K., Iida M., Koike H., Sakamoto K., Hara Y., Kuru S., Kadomatsu K., Shimamura T., Ogi T., Katsuno M.

    Metabolome and transcriptome analysis on muscle of sporadic inclusion body myositis

    Annals of Clinical and Translational Neurology

    https://doi.org/10.1002/acn3.51657

  • Annals of Clinical and Translational Neurology

    Establishment of induced pluripotent stem cells from a patient with 16p13.11 duplication and VPS13B deletion

    Stem Cell Research

    https://doi.org/10.1016/j.scr.2022.102884

  • Go S., Sato C., Hane M., Go S., Kitajima K.

    Implication of N-glycolylneuraminic acid in regulation of cell adhesiveness of C2C12 myoblast cells during differentiation into myotube cells

    Glycoconjugate Journal

    https://doi.org/1007.10719/s022-10049-9

  • Hagino R., Mozaki K., Komura N., Imamura A., Ishida H., Ando H., Tanaka H.-N.

    Straightforward Synthesis of the Poly(ADP-ribose) Branched Core Structure

    ACS Omega

    https://doi.org/10.1021/acsomega.2c04732

  • Yoshida Y., Zheng T., Tanabe W., Tomoike F., Hashiya F., Suzuki T., Hirota S., Saiki Y., Horii A., Hirayama A., Soga T., Kimura Y., Abe H.

    Development of Fluorophosphoramidate as a Biocompatibly Transformable Functional Group and its Application as a Phosphate Prodrug for Nucleoside Analogs

    ChemMedChem

    https://doi.org/10.1002/cmdc.202200188

  • Tsukada F., Takashima S., Wakihara Y., Kamatari Y.O., Shimizu K., Okada A., Inoshima Y.

    Characterization of miRNAs in Milk Small Extracellular Vesicles from Enzootic Bovine Leukosis Cattle

    International Journal of Molecular Sciences

    https://doi.org/10.3390/ijms231810782

  • Wen P., Chen J., Zuo C., Gao X., Fujita M., Yang G.

    Proteome and Glycoproteome Analyses Reveal the Protein N-Linked Glycosylation Specificity of STT3A and STT3B

    Cells

    https://doi.org/10.3390/cells11182775

  • Osada N., Nagae M., Nakano M., Hirata T., Kizuka Y.

    Examination of differential glycoprotein preferences of N-acetylglucosaminyltransferase-IV isozymes a and b

    Journal of Biological Chemistry

    https://doi.org/1016.2022/j.jbc.102400

  • Yan M., Komatsu N., Muro R., Huynh N.C.-N., Tomofuji Y., Okada Y., Suzuki H.I., Takaba H., Kitazawa R., Kitazawa S., Pluemsakunthai W., Mitsui Y., Satoh T., Okamura T., Nitta T., Im S.-H., Kim C.J., Kollias G., Tanaka S., Okamoto K., Tsukasaki M., Takayanagi H.

    ETS1 governs pathological tissue-remodeling programs in disease-associated fibroblasts

    Nature Immunology

    https://doi.org/1038.41590/s022-01285-0

  • Takashima S., Fujita H., Toyoshi K., Ohba A., Hirata Y., Shimozawa N., Oh-hashi K.

    Hypomorphic mutation of PEX3 with peroxisomal mosaicism reveals the oscillating nature of peroxisome biogenesis coupled with differential metabolic activities

    Molecular Genetics and Metabolism

    https://doi.org/10.1016/j.ymgme.2022.07.008

  • Kushima I., Nakatochi M., Aleksic B., Okada T., Kimura H., Kato H., Morikawa M., Inada T., Ishizuka K., Torii Y., Nakamura Y., Tanaka S., Imaeda M., Takahashi N., Yamamoto M., Iwamoto K., Nawa Y., Ogawa N., Iritani S., Hayashi Y., Lo T., Otgonbayar G., Furuta S., Iwata N., Ikeda M., Saito T., Ninomiya K., Okochi T., Hashimoto R., Yamamori H., Yasuda Y., Fujimoto M., Miura K., Itokawa M., Arai M., Miyashita M., Toriumi K., Ohi K., Shioiri T., Kitaichi K., Someya T., Watanabe Y., Egawa J., Takahashi T., Suzuki M., Sasaki T., Tochigi M., Nishimura F., Yamasue H., Kuwabara H., Wakuda T., Kato T.A., Kanba S., Horikawa H., Usami M., Kodaira M., Watanabe K., Yoshikawa T., Toyota T., Yokoyama S., Munesue T., Kimura R., Funabiki Y., Kosaka H., Jung M., Kasai K., Ikegame T., Jinde S., Numata S., Kinoshita M., Kato T., Kakiuchi C., Yamakawa K., Suzuki T., Hashimoto N., Ishikawa S., Yamagata B., Nio S., Murai T., Son S., Kunii Y., Yabe H., Inagaki M., Goto Y.-I., Okumura Y., Ito T., Arioka Y., Mori D., Ozaki N.

    Cross-Disorder Analysis of Genic and Regulatory Copy Number Variations in Bipolar Disorder, Schizophrenia, and Autism Spectrum Disorder

    Biological Psychiatry

    https://doi.org/10.1016/j.biopsych.2022.04.003

  • Kushima I., Imaeda M., Tanaka S., Kato H., Oya-Ito T., Nakatochi M., Aleksic B., Ozaki N.

    Contribution of copy number variations to the risk of severe eating disorders

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13430

  • Morikawa C., Sugiura K., Kondo K., Yamamoto Y., Kojima Y., Ozawa Y., Yoshioka H., Miura N., Piao J., Okada K., Hanamatsu H., Tsuda M., Tanaka S., Furukawa J.-I., Shinohara Y.

    Evaluation of the context of downstream N- and free N-glycomic alterations induced by swainsonine in HepG2 cells

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2022.130168

  • Nakagawa Y., Oya Y., Ojika M., Igarashi Y., Ito Y.

    Chemical modification of pradimicin A to suppress aggregation without impairing D-mannose-binding and antifungal activities

    Tetrahedron

    https://doi.org/10.1016/j.tet.2022.132919

  • Higashi S.L., Shintani Y., Ikeda M.

    Installing Reduction Responsiveness into Biomolecules by Introducing Nitroaryl Groups

    Chemistry – A European Journal

    https://doi.org/10.1002/chem.202201103

  • Wu D., Gilormini P.-A., Toda S., Biot C., Lion C., Guérardel Y., Sato C., Kitajima K.

    A novel C-domain-dependent inhibition of the rainbow trout CMP-sialic acid synthetase activity by CMP-deaminoneuraminic acid

    Biochemical and Biophysical Research Communications

    https://doi.org/10.1016/j.bbrc.2022.05.031

     

  • Tsuchiya A., Kobayashi M., Kamatari Y.O., Mitsunaga T., Yamauchi K.

    Development of flavonoid probes and the binding mode of the target protein and quercetin derivatives

    Bioorganic and Medicinal Chemistry

    https://doi.org/10.1016/j.bmc.2022.116854

  • Hirata T., Takata M., Tokoro Y., Nakano M., Kizuka Y.

    Shedding of N-acetylglucosaminyltransferase-V is regulated by maturity of cellular N-glycan

    Communications biology

    https://doi.org/10.1038/s42003-022-03697-y

  • Hamaya Y., Komura N., Imamura A., Ishida H., Ando H., Tanaka H.-N.

    Protecting-group- and microwave-free synthesis of β-glycosyl esters and aryl β-glycosides of N-acetyl-D-glucosamine

    Bioorganic and Medicinal Chemistry

    https://doi.org/10.1016/j.bmc.2022.116852

  • Segi N., Ozaki T., Suzuki Y., Ouchida J., Imagama S., Kadomatsu K., Sakamoto K.

    Close association of polarization and LC3, a marker of autophagy, in axon determination in mouse hippocampal neurons

    Experimental Neurology

    https://doi.org/10.1016/j.expneurol.2022.114112

  • Nishiguchi S., Furuta T., Uchihashi T.

    Multiple dimeric structures and strand-swap dimerization of E-cadherin in solution visualized by high-speed atomic force microscopy

    Proceedings of the National Academy of Sciences of the United States of America

    https://doi.org/10.1073/pnas.2208067119

  • Tsukamoto Y., Ogawa M., Yogi K., Tashima Y., Takeuchi H., Okajima T.

    Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH1

    Glycobiology

    https://doi.org/10.1093/glycob/cwac015

  • Kushima I., Uematsu M., Ishizuka K., Aleksic B., Ozaki N.

    Psychiatric patients with a de novo 17q12 deletion: Two case reports

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13367

  • Abe N., Imaeda A., Inagaki M., Li Z., Kawaguchi D., Onda K., Nakashima Y., Uchida S., Hashiya F., Kimura Y., Abe H.

    Complete Chemical Synthesis of Minimal Messenger RNA by Efficient Chemical Capping Reaction

    ACS Chemical Biology

    https://doi.org/10.1021/acschembio.1c00996

  • Hatanaka R., Araki E., Hane M., Go S., Wu D., Kitajima K., Sato C.

    The α2,8-sialyltransferase 6 (St8sia6) localizes in the ER and enhances the anchorage-independent cell growth in cancer

    Biochemical and Biophysical Research Communications

    https://doi.org/10.1016/j.bbrc.2022.03.146

  • Tanaka S., Morita M., Yamagishi T., Madapally H.V., Hayashida K., Khandelia H., Gerle C., Shigematsu H., Oshima A., Abe K.

    Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump

    Journal of medicinal chemistry

    https://doi.org/10.1021/acs.jmedchem.2c00338

     

  • Umezawa F., Natsume M., Fukusada S., Nakajima K., Yamasaki F., Kawashima H., Kuo C.-W., Khoo K.-H., Shimura T., Yagi H., Kato K.

    Cancer Malignancy Is Correlated with Upregulation of PCYT2-Mediated Glycerol Phosphate Modification of α-Dystroglycan

    International Journal of Molecular Sciences

    https://doi.org/10.3390/ijms23126662

  • Ito K.N., Isobe K., Osakada F.

    Fast z-focus controlling and multiplexing strategies for multiplane two-photon imaging of neural dynamics

    Neuroscience Research

    https://doi.org/10.1016/j.neures.2022.03.007

  • Vibhute A.M., Tanaka H.-N., Mishra S.K., Osuka R.F., Nagae M., Yonekawa C., Korekane H., Doerksen R.J., Ando H., Kizuka Y.

    Structure-based design of UDP-GlcNAc analogs as candidate GnT-V inhibitors

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2022.130118

  • Shibata A., Higashi S.L., Ikeda M.

    Nucleic acid-based fluorescent sensor systems: a review

    Polymer Journal

    https://doi.org/10.1038/s41428-022-00623-1

  • Wang Y., Kanie K., Takezawa T., Horikawa M., Kaneko K., Sugimoto A., Yamawaki-Ogata A., Narita Y., Kato R.

    Bi-layered carboxymethyl cellulose-collagen vitrigel dual-surface adhesion-prevention membrane

    Carbohydrate Polymers

    https://doi.org/10.1016/j.carbpol.2022.119223

  • Takahashi M., Komura N., Yoshida Y., Yamaguchi E., Hasegawa A., Tanaka H.-N., Imamura A., Ishida H., Suzuki K.G.N., Ando H.

    Development of lacto-series ganglioside fluorescent probe using late-stage sialylation and behavior analysis with single-molecule imaging

    RSC Chemical Biology

    https://doi.org/10.1039/d2cb00083k

  • Daher W., Leclercq L.-D., Johansen M.D., Hamela C., Karam J., Trivelli X., Nigou J., Guérardel Y., Kremer L.

    Glycopeptidolipid glycosylation controls surface properties and pathogenicity in Mycobacterium abscessus

    Cell Chemical Biology

    https://doi.org/10.1016/j.chembiol.2022.03.008

  • Higashi S.L., Isogami A., Takahashi J., Shibata A., Hirosawa K.M., Suzuki K.G.N., Sawada S., Tsukiji S., Matsuura K., Ikeda M.

    Construction of a Reduction-responsive DNA Microsphere using a Reduction-cleavable Spacer based on a Nitrobenzene Scaffold

    Chemistry – An Asian Journal

    https://doi.org/10.1002/asia.202200142

  • Hane M., Kitajima K., Sato C.

    Comprehensive Analysis of Oligo/Polysialylglycoconjugates in Cancer Cell Lines

    International Journal of Molecular Sciences

    https://doi.org/10.3390/ijms23105569

  • Toyama M., Takasaki Y., Branko A., Kimura H., Kato H., Nawa Y., Kushima I., Ishizuka K., Shimamura T., Ogi T., Ozaki N.

    Exome sequencing of Japanese schizophrenia multiplex families supports the involvement of calcium ion channels

    PLoS ONE

    https://doi.org/10.1371/journal.pone.0268321

  • Takahashi Y., Abe C., Hane M., Wu D., Kitajima K., Sato C.

    Polysialylation in a DISC1 Mutant Mouse

    International Journal of Molecular Sciences

    https://doi.org/10.3390/ijms23095207

  • Kimura S., Kamishina H., Hirata Y., Furuta K., Furukawa Y., Yamato O., Maeda S., Kamatari Y.O.

    Novel oxindole compounds inhibit the aggregation of amyloidogenic proteins associated with neurodegenerative diseases

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2022.130114

  • Masaki Y., Yamaguchi M., Takeuchi R.F., Osakada F.

    Monosynaptic rabies virus tracing from projection-targeted single neurons

    Neuroscience Research

    https://doi.org/10.1016/j.neures.2022.01.007

  • Hirata T., Takekiyo T., Yoshimura Y., Tokoro Y., Ishizaki T., Kizuka Y., Kuroda K.

    Cryostorage of unstable N-acetylglucosaminyltransferase-V by synthetic zwitterions

    RSC Advances

    https://doi.org/10.1039/d2ra01575g

  • Hasegawa Y., Motoyama M., Hamamoto A., Kimura S., Kamatari Y.O., Kamishina H., Oh-Hashi K., Furuta K., Hirata Y.

    Identification of Novel Oxindole Compounds That Suppress ER Stress-Induced Cell Death as Chemical Chaperones

    ACS Chemical Neuroscience

    https://doi.org/10.1021/acschemneuro.2c00064

  • Mery A., Jawhara S., François N., Cornu M., Poissy J., Martinez-Esparza M., Poulain D., Sendid B., Guerardel Y.

    Identification of fungal trehalose for the diagnosis of invasive candidiasis by mass spectrometry

    Biochimica et Biophysica Acta – General Subjects

    https://doi.org/10.1016/j.bbagen.2022.130083

  • Araki E., Hane M., Hatanaka R., Kimura R., Tsuda K., Konishi M., Komura N., Ando H., Kitajima K., Sato C.

    Analysis of biochemical features of ST8 α-N-acetyl-neuraminide α2,8-sialyltransferase (St8sia) 5 isoforms

    Glycoconjugate Journal

    https://doi.org/10.1007/s10719-021-10034-8

  • Suga H., Okumura R., Ikawa M., Shimizu M., Kageyama K.

    A natural two-nucleotide deletion affirms role for NADPH oxidase in pathogenicity and perithecium formation in Fusarium graminearum species complex

    Plant Pathology

    https://doi.org/10.1111/ppa.13499

  • Kudo Y., Endo S., Fujita M., Ota A., Kamatari Y.O., Tanaka Y., Ishikawa T., Ikeda H., Okada T., Toyooka N., Fujimoto N., Matsunaga T., Ikari A.

    Discovery and Structure-Based Optimization of Novel Atg4B Inhibitors for the Treatment of Castration-Resistant Prostate Cancer

    Journal of Medicinal Chemistry

    https://doi.org/10.1021/acs.jmedchem.1c02113

  • Yan S., Hodžić A., Bandini G., Yang G., Vanbeselaere J., Guérardel Y.

    Characterization, Biosynthesis and Biological Functions of Novel Glyco-Epitopes

    Frontiers in Molecular Biosciences

    https://doi.org/10.3389/fmolb.2022.871037

  • Akıl C., Ali S., Tran L.T., Gaillard J., Li W., Hayashida K., Hirose M., Kato T., Oshima A., Fujishima K., Blanchoin L., Narita A., Robinson R.C.

    Structure and dynamics of Odinarchaeota tubulin and the implications for eukaryotic microtubule evolution

    Science Advances

    https://doi.org/10.1126/sciadv.abm2225

  • Oka N., Kanda M., Furuzawa M., Arai W., Ando K.

    Synthesis of Truncated Carbocyclic Nucleosides Using 5′-Deoxy-5′-Heteroarylsulfonylnucleosides

    Current Protocols

    https://doi.org/10.1002/cpz1.398

  • Seo N., Nakamura J., Kaneda T., Tateno H., Shimoda A., Ichiki T., Furukawa K., Hirabayashi J., Akiyoshi K., Shiku H.

    Distinguishing functional exosomes and other extracellular vesicles as a nucleic acid cargo by the anion-exchange method

    Journal of Extracellular Vesicles

    https://doi.org/10.1002/jev2.12205

  • Wang W., Okajima T., Takeuchi H.

    Significant Roles of Notch O-Glycosylation in Cancer

    Molecules

    https://doi.org/10.3390/molecules27061783

  • Hirata T., Kobayashi A., Furuse T., Yamada I., Tamura M., Tomita H., Tokoro Y., Ninomiya A., Fujihara Y., Ikawa M., Maeda Y., Murakami Y., Kizuka Y., Kinoshita T.

    Loss of the N-acetylgalactosamine side chain of the GPI-anchor impairs bone formation and brain functions and accelerates the prion disease pathology

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2022.101720

  • Osuka R.F., Hirata T., Nagae M., Nakano M., Shibata H., Okamoto R., Kizuka Y.

    N-acetylglucosaminyltransferase-V requires a specific noncatalytic luminal domain for its activity toward glycoprotein substrates

    Journal of Biological Chemistry

    https://doi.org/10.1016/j.jbc.2022.101666

  • Matsui Y., Abe Y., Uno K., Miyano S.

    RoDiCE: Robust differential protein co-expression analysis for cancer complexome

    Bioinformatics

    https://doi.org/10.1093/bioinformatics/btab612

  • Kuzuya M., Hirano H., Hayashida K., Watanabe M., Kobayashi K., Terada T., Mahmood M.I., Tama F., Tani K., Fujiyoshi Y., Oshima A.

    Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids

    Science Signaling

    https://doi.org/10.1126/scisignal.abg6941

  • Shintani Y., Ohtomi T., Shibata A., Kitamura Y., Hirosawa K.M., Suzuki K.G.N., Ikeda M.

    Formation of Supramolecular Nanostructures through in Situ Self-Assembly and Post-Assembly Modification of a Biocatalytically Constructed Dipeptide Hydrazide

    Chemistry – A European Journal

    https://doi.org/10.1002/chem.202104421

  • Li F.J., Komura R., Nakashima C., Shimizu M., Kageyama K., Suga H.

    Molecular Diagnosis of Thiophanate-Methyl-Resistant Strains of Fusarium fujikuroi in Japan

    Plant Disease

    https://doi.org/10.1094/PDIS-07-21-1501-RE

  • Vu H., Muto Y., Hayashi M., Noguchi H., Tanaka K., Yamamoto Y.

    Complete Genome Sequences of Three Phocaeicola vulgatus Strains Isolated from a Healthy Japanese Individual

    Microbiology Resource Announcements

    https://doi.org/10.1128/mra.01124-21

  • Oda M., Sano T., Kamatari Y.O., Abe Y., Ikura T., Ito N.

    Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH

    Protein Journal

    https://doi.org/10.1007/s10930-021-10036-3

  • Ozaki H., Asano T., Tanaka H.-N., Komura N., Ando H., Ishida H., Imamura A.

    Blockwise synthesis of polylactosamine fragments and keratan sulfate oligosaccharides comprised of dimeric Galβ(1 → 4)GlcNAc6Sβ

    Carbohydrate Research

    https://doi.org/10.1016/j.carres.2022.108502

  • Miyanishi W., Ojika M., Akase D., Aida M., Igarashi Y., Ito Y., Nakagawa Y.

    D-Mannose binding, aggregation property, and antifungal activity of amide derivatives of pradimicin A

    Bioorganic and Medicinal Chemistry

    https://doi.org/10.1016/j.bmc.2021.116590

  • Suzuki H.I., Onimaru K.

    Biomolecular condensates in cancer biology

    Cancer Science

    https://doi.org/10.1111/cas.15232

  • Sugiura S., Shintani Y., Mori D., Higashi S.L., Shibata A., Kitamura Y., Kawano S.-I., Hirosawa K.M., Suzuki K.G.N., Ikeda M.

    Design of supramolecular hybrid nanomaterials comprising peptide-based supramolecular nanofibers and in situ generated DNA nanoflowers through rolling circle amplification

    Nanoscale

    https://doi.org/10.1039/d2nr04556g

  • Suzuki K., Nishio N., Kimura H., Tokura T., Kishi S., Ozaki N., Fujimoto Y., Sone M.

    Comparison of quality of life and psychological distress in patients with tongue cancer undergoing a total/subtotal glossectomy or extended hemiglossectomy and free flap transfer: a prospective evaluation

    International Journal of Oral and Maxillofacial Surgery

    https://doi.org/10.1016/j.ijom.2022.11.010

  • Lo T., Kushima I., Aleksic B., Yoshimi A., Someya T., Watanabe Y., Ozaki N.

    Clinical manifestations of schizophrenia in four patients with variants in voltage-gated calcium channel-encoding genes: a case series

    Psychiatry and Clinical Neurosciences

    https://doi.org/10.1111/pcn.13494

  • Ando H., Komura N., Tanaka H.-N., Imamura A., Ishida H.

    Chemical synthesis of sialoglyco-architectures

    Advances in Carbohydrate Chemistry and Biochemistry

    https://doi.org/10.1016/bs.accb.2022.09.003

  • Kato H., Kimura H., Kushima I., Takahashi N., Aleksic B., Ozaki N.

    The genetic architecture of schizophrenia: review of large-scale genetic studies

    Journal of Human Genetics

    https://doi.org/10.1038/s10038-022-01059-4

  • Ma C., Tsukamoto Y., Takeuchi H.

    Generation of Properly Folded Epidermal Growth Factor-Like (EGF) Repeats and Glycosyltransferases Enables In Vitro O-Glycosylation

    Methods in Molecular Biology

    https://doi.org/10.1007/978-1-0716-2201-8_3

  • Yoshino S., Suzuki H.I.

    The molecular understanding of super-enhancer dysregulation in cancer

    Nagoya Journal of Medical Science

    https://doi.org/10.18999/nagjms.84.2.216

  • Kataoka K., Suzuki S., Tenno T., Goda N., Hibino E., Oshima A., Hiroaki H.

    A cryptic phosphate-binding pocket on the SPFH domain of human stomatin that regulates a novel fibril-like self-assembly

    Current Research in Structural Biology

    https://doi.org/10.1016/j.crstbi.2022.05.002

  • Horii Y., Okadera K., Miyawaki S., Shiina T., Shimizu Y.

    Suncus murinus as a novel model animal that is suitable for elucidating the mechanism of daily torpor

    Biomedical Research (Japan)

    https://doi.org/10.2220/biomedres.43.53

  • Hu D., Hirabayashi J.

    Transformation of Agrocybe cylindracea Galectin into αGalNAc-Specific Lectin

    Methods in Molecular Biology

    https://doi.org/10.1007/978-1-0716-2055-7_14

  • Nakagawa Y., Ito Y.

    Mannose-binding analysis and biological application of pradimicins

    Proceedings of the Japan Academy Series B: Physical and Biological Sciences

    https://doi.org/10.2183/pjab.98.002

2021年

  • Tseng H.-C., Hsiao C.-T., Yamakawa N., Guérardel Y., Khoo K.-H.

    Discovery Sulfoglycomics and Identification of the Characteristic Fragment Ions for High-Sensitivity Precise Mapping of Adult Zebrafish Brain–Specific Glycotopes

    Frontiers in Molecular Biosciences

    doi: https://doi.org/10.3389/fmolb.2021.771447

  • Oka N., Hirabayashi H., Kumada K., Ando K.

    Synthesis of xanthosine 2-phosphate diesters via phosphitylation of the carbonyl group

    Bioorganic and Medicinal Chemistry Letters

    doi: https://doi.org/10.1016/j.bmcl.2021.128439

  • Hiraoka H., Shu Z., Tri Le B., Masuda K., Nakamoto K., Fangjie L., Abe N., Hashiya F., Kimura Y., Shimizu Y., Veedu R.N., Abe H.

    Antisense Oligonucleotide Modified with Disulfide Units Induces Efficient Exon Skipping in mdx Myotubes through Enhanced Membrane Permeability and Nucleus Internalization

    ChemBioChem

    doi: https://doi.org/10.1002/cbic.202100413

  • Oka N., Kanda M., Furuzawa M., Arai W., Ando K.

    Serendipitous One-Step Synthesis of Cyclopentene Derivatives from 5′-Deoxy-5′-heteroarylsulfonylnucleosides as Nucleoside-Derived Julia-Kocienski Reagents

    Journal of Organic Chemistry

    doi: https://doi.org/10.1021/acs.joc.1c01940

  • Yamaoka K., Oikawa R., Abe N., Nakamoto K., Tomoike F., Hashiya F., Kimura Y., Abe H.

    Completely Chemically Synthesized Long DNA Can be Transcribed in Human Cells

    ChemBioChem

    doi: https://doi.org/10.1002/cbic.202100312

  • Hayakawa T., Terahara M., Fujito N.T., Matsunaga T., Teshima K.M., Hane M., Kitajima K., Sato C., Takahata N., Satta Y.

    Lower promoter activity of the ST8SIA2 gene has been favored in evolving human collective brains

    PLoS ONE

    doi: https://doi.org/10.1371/journal.pone.0259897

  • Ogami K., Suzuki H.I.

    Nuclear rna exosome and pervasive transcription: Dual sculptors of genome function

    International Journal of Molecular Sciences

    doi: https://doi.org/10.3390/ijms222413401

  • Wu D., Arakawa H., Fujita A., Hashimoto H., Hibi M., Naruse K., Kamei Y., Sato C., Kitajima K.

    A point-mutation in the C-domain of CMP-sialic acid synthetase leads to lethality of medaka due to protein insolubility

    Scientific Reports

    doi: https://doi.org/10.1038/s41598-021-01715-3

  • Nagai R., Sugimachi A., Tanimoto Y., Suzuki K.G.N., Hayashi F., Weikert D., Gmeiner P., Kasai R.S., Morigaki K.

    Functional Reconstitution of Dopamine D2 Receptor into a Supported Model Membrane in a Nanometric Confinement

    Advanced Biology

    doi: https://doi.org/10.1002/adbi.202100636

  • Yagi-Utsumi M., Aoki K., Watanabe H., Song C., Nishimura S., Satoh T., Yanaka S., Ganser C., Tanaka S., Schnapka V., Goh E.W., Furutani Y., Murata K., Uchihashi T., Arakawa K., Kato K.

    Desiccation-induced fibrous condensation of CAHS protein from an anhydrobiotic tardigrade

    Scientific Reports

    doi: https://doi.org/10.1038/s41598-021-00724-6

  • Oka N., Suzuki K., Mori A., Ando K.

    Stereoselective Synthesis of 1,2-cis-Glycosyl Sulfones and Their Application in One-Pot Julia Olefination for the Synthesis of exo-Glycals

    European Journal of Organic Chemistry

    doi: https://doi.org/10.1002/ejoc.202101202

  • Machino M., Gong Y., Ozaki T., Suzuki Y., Watanabe E., Imagama S., Kadomatsu K., Sakamoto K.

    Dermatan sulphate is an activating ligand of anaplastic lymphoma kinase

    Journal of Biochemistry

    doi: https://doi.org/10.1093/jb/mvab085

  • Inden M., Takagi A., Kitai H., Ito T., Kurita H., Honda R., Kamatari Y.O., Nozaki S., Wen X., Hijioka M., Kitamura Y., Hozumi I.

    Kaempferol has potent protective and antifibrillogenic effects for α-synuclein neurotoxicity in vitro

    International Journal of Molecular Sciences

    doi: https://doi.org/10.3390/ijms222111484

  • Sivignon A., Yu S.-Y., Ballet N., Vandekerckove P., Barnich N., Guerardel Y.

    Heteropolysaccharides from S. cerevisiae show anti-adhesive properties against E. coli associated with Crohn’s disease

    Carbohydrate Polymers

    doi: https://doi.org/10.1016/j.carbpol.2021.118415

  • Vibhute A.M., Komura N., Tanaka H.-N., Imamura A., Ando H.

    Advanced Chemical Methods for Stereoselective Sialylation and Their Applications in Sialoglycan Syntheses

    Chemical Record

    doi: https://doi.org/10.1002/tcr.202100080

  • Komura K., Inamoto T., Tsujino T., Matsui Y., Konuma T., Nishimura K., Uchimoto T., Tsutsumi T., Matsunaga T., Maenosono R., Yoshikawa Y., Taniguchi K., Tanaka T., Uehara H., Hirata K., Hirano H., Nomi H., Hirose Y., Ono F., Azuma H.

    Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents

    Oncogene

    doi: https://doi.org/10.1038/s41388-021-02021-y

  • Fukuo H., Suzuki T., Shimabukuro J., Komura N., Tanaka H.-N., Imamura A., Ishida H., Ando H.

    Synthesis of Diverse Seleno-Glycolipids via the Transacetalization of Selenoacetals

    European Journal of Organic Chemistry

    doi: https://doi.org/10.1002/ejoc.202100847

  • Higashi S.L., Ikeda M.

    Development of an Amino Sugar-Based Supramolecular Hydrogelator with Reduction Responsiveness

    Journal of the American Chemical Society

    doi: https://doi.org/10.1021/jacsau.1c00270

  • Nakagawa Y., Kakihara S., Tsuzuki K., Ojika M., Igarashi Y., Ito Y.

    A Pradimicin-Based Staining Dye for Glycoprotein Detection

    Journal of Natural Products

    doi: https://doi.org/10.1021/acs.jnatprod.1c00506

  • Kawade H., Morise J., Mishra S.K., Tsujioka S., Oka S., Kizuka Y.

    Tissue-specific regulation of hnk-1 biosynthesis by bisecting glcnac

    Molecules

    doi: https://doi.org/10.3390/molecules26175176

  • García-Jiménez M.J., Gil-Caballero S., Maza S., Corzana F., Juárez-Vicente F., Miles J.R., Sakamoto K., Kadomatsu K., García-Domínguez M., de Paz J.L., Nieto P.M.

    Midkine Interaction with Chondroitin Sulfate Model Synthetic Tetrasaccharides and Their Mimetics: The Role of Aromatic Interactions

    Chemistry – A European Journal

    doi: https://doi.org/10.1002/chem.202101674

  • Miyazawa K., Itoh S.G., Watanabe H., Uchihashi T., Yanaka S., Yagi-Utsumi M., Kato K., Arakawa K., Okumura H.

    Tardigrade Secretory-Abundant Heat-Soluble Protein Has a Flexible β-Barrel Structure in Solution and Keeps This Structure in Dehydration

    Journal of Physical Chemistry B

    doi: https://doi.org/10.1021/acs.jpcb.1c04850

  • Dasgupta B., Miyashita O., Uchihashi T., Tama F.

    Reconstruction of Three-Dimensional Conformations of Bacterial ClpB from High-Speed Atomic-Force-Microscopy Images

    Frontiers in Molecular Biosciences

    doi: https://doi.org/10.3389/fmolb.2021.704274

  • Ohkawa Y., Kizuka Y., Takata M., Nakano M., Ito E., Mishra S.K., Akatsuka H., Harada Y., Taniguchi N.

    Peptide sequence mapping around bisecting glcnac‐bearing n‐glycans in mouse brain

    International Journal of Molecular Sciences

    doi: https://doi.org/10.3390/ijms22168579

  • Nakano M., Hanashima S., Hara T., Kabayama K., Asahina Y., Hojo H., Komura N., Ando H., Nyholm T.K.M., Slotte J.P., Murata M.

    FRET detects lateral interaction between transmembrane domain of EGF receptor and ganglioside GM3 in lipid bilayers

    Biochimica et Biophysica Acta – Biomembranes

    doi: https://doi.org/10.1016/j.bbamem.2021.183623

  • Ohashi S., Hashiya F., Abe H.

    Variety of Nucleotide Polymerase Mutants Aiming to Synthesize Modified RNA

    ChemBioChem

    doi: https://doi.org/10.1002/cbic.202100004

  • Shirakami N., Kawaki Y., Higashi S.L., Shibata A., Kitamura Y., Hanifah S.A., Wah L.L., Ikeda M.

    Introduction of an Oxidation-responsive 4-Boronobenzyl Group into an Oligonucleotide through a Postmodification Approach

    Chemistry Letters

    doi: https://doi.org/10.1246/cl.210204

  • Sakai S., Watanabe S., Komine O., Sobue A., Yamanaka K.

    Novel reporters of mitochondria-associated membranes (MAM), MAMtrackers, demonstrate MAM disruption as a common pathological feature in amyotrophic lateral sclerosis

    FASEB Journal

    doi: https://doi.org/10.1096/fj.202100137R

  • Takashima S., Takemoto S., Toyoshi K., Ohba A., Shimozawa N.

    Zebrafish model of human Zellweger syndrome reveals organ-specific accumulation of distinct fatty acid species and widespread gene expression changes

    Molecular Genetics and Metabolism

    doi: https://doi.org/10.1016/j.ymgme.2021.05.002

  • Kizuka Y.

    The Involvement of Cellular Glycans in Alzheimer’s Disease

    Comprehensive Glycoscience: Second Editition

    doi: https://doi.org/10.1016/B978-0-12-819475-1.00002-X

  • Ohkawa Y., Kizuka Y., Harada Y., Taniguchi N.

    Glycans in Chronic Obstructive Pulmonary Disease (COPD)

    Comprehensive Glycoscience: Second Edition

    doi: https://doi.org/10.1016/B978-0-12-819475-1.00030-4

  • Sakamoto K., Ozaki T., Kadomatsu K.

    Axonal Regeneration by Glycosaminoglycan

    Frontiers in Cell and Developmental Biology

    doi: https://oi.org/10.3389/fcell.2021.702179

  • Sheikh A.A.D., Akatsu C., Abdu-Allah H.H.M., Suganuma Y., Imamura A., Ando H., Takematsu H., Ishida H., Tsubata T.

    The protein tyrosine phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) is essential for the ligand-mediated regulation of CD22 in BCR-ligated b cells

    Journal of Immunology

    doi: https://doi.org/10.4049/jimmunol.2100109

  • Sakamoto K., Ozaki T., Suzuki Y., Kadomatsu K.

    Type IIa RPTPs and glycans: Roles in axon regeneration and synaptogenesis

    International Journal of Molecular Sciences

    doi: https://doi.org/10.3390/ijms22115524

  • Yang J., Hirata T., Liu Y.-S., Guo X.-Y., Gao X.-D., Kinoshita T., Fujita M.

    Human SND2 mediates ER targeting of GPI-anchored proteins with low hydrophobic GPI attachment signals

    FEBS Letters

    doi: https://doi.org/10.1002/1873-3468.14083

  • Ito S., Ozaki T., Morozumi M., Imagama S., Kadomatsu K., Sakamoto K.

    Enoxaparin promotes functional recovery after spinal cord injury by antagonizing PTPRσ

    Experimental Neurology

    doi: https://doi.org/10.1016/j.expneurol.2021.113679

  • Shirakami N., Higashi S.L., Kawaki Y., Kitamura Y., Shibata A., Ikeda M.

    Construction of a reduction-responsive oligonucleotide via a post-modification approach utilizing 4-nitrophenyl diazomethane

    Polymer Journal

    doi: https://doi.org/10.1038/s41428-021-00464-4

  • Sato C., Kitajima K.

    Polysialylation and disease

    Molecular Aspects of Medicine

    doi: https://doi.org/10.1016/j.mam.2020.100892

  • Huang Y.-F., Aoki K., Akase S., Ishihara M., Liu Y.-S., Yang G., Kizuka Y., Mizumoto S., Tiemeyer M., Gao X.-D., Aoki-Kinoshita K.F., Fujita M.

    Global mapping of glycosylation pathways in human-derived cells

    Developmental Cell

    doi: https://doi.org/10.1016/j.devcel.2021.02.023

  • Yoshida Y., Honma M., Kimura Y., Abe H.

    Structure, Synthesis and Inhibition Mechanism of Nucleoside Analogues as HIV-1 Reverse Transcriptase Inhibitors (NRTIs)

    ChemMedChem

    doi: https://doi.org/10.1002/cmdc.202000695

  • Kawanishi K., Saha S., Diaz S., Vaill M., Sasmal A., Siddiqui S.S., Choudhury B., Sharma K., Chen X., Schoenhofen I.C., Sato C., Kitajima K., Freeze H.H., Münster-Kühnel A., Varki A.

    Evolutionary conservation of human ketodeoxynonulosonic acid production is independent of sialoglycan biosynthesis

    Journal of Clinical Investigation

    doi: https://doi.org/10.1172/JCI137681

  • Ohtomi T., Higashi S.L., Mori D., Shibata A., Kitamura Y., Ikeda M.

    Effect of side chain phenyl group on the self-assembled morphology of dipeptide hydrazides

    Peptide Science

    doi: https://doi.org/10.1002/pep2.24200

  • Barua R., Mizuno K., Tashima Y., Ogawa M., Takeuchi H., Taguchi A., Okajima T.

    Bioinformatics and functional analyses implicate potential roles for EOGT and L-fringe in pancreatic cancers

    Molecules

    doi: https://doi.org/10.3390/molecules26040882

  • Gong Y., Abudureyimu S., Kadomatsu K., Sakamoto K.

    Identification of PTPRσ-interacting proteins by proximity-labelling assay

    Journal of Biochemistry

    doi: https://doi.or/10.1093/jb/mvaa141

  • Saiki W., Ma C., Okajima T., Takeuchi H.

    Current views on the roles of o‐glycosylation in controlling notch‐ligand interactions

    Biomolecules

    doi: https://doi.org/10.3390/biom11020309

  • Vu H., Hayashi M., Nguyen T.N., Khong D.T., Tran H.T., Yamamoto Y., Tanaka K.

    Comparison of Phenotypic and Genotypic Patterns of Antimicrobial-Resistant Bacteroides fragilis Group Isolated from Healthy Individuals in Vietnam and Japan

    Infection and Drug Resistance

    doi: https://doi.org/10.2147/IDR.S341571

  • Onishi Y., Mise K., Kawakita C., Uchida H.A., Sugiyama H., Sugawara R., Yamaguchi S., Yoshida M., Mitsuhashi T., Yamada M., Hirabayashi J., Wada J.

    Development of Urinary Diagnostic Biomarker for IgA Nephropathy by Lectin Microarray

    American Journal of Nephrology

    doi: https://doi.org/10.1159/000520998

  • Jing L.F., Suga H.

    Various methods for controlling the bakanae disease in rice

    Reviews in Agricultural Science

    doi: https://doi.org/10.1159/000520998

  • Harada Y., Ohkawa Y., Maeda K., Kizuka Y., Taniguchi N.

    Extracellular Vesicles and Glycosylation

    Advances in Experimental Medicine and Biology

    doi: https://doi.org/10.1007/978-3-030-70115-4_6

  • Hirata T., Kizuka Y.

    N-Glycosylation

    Advances in Experimental Medicine and Biology

    doi: https://doi.org/10.1007/978-3-030-70115-4_1

  • Komata Y., Tsubota S., Sakamoto K., Ikematsu S., Kadomatsu K.

    Screening of novel Midkine binding protein by BioID2-based proximity labeling

    Nagoya Journal of Medical Science

    doi: https://doi.org/10.18999/nagjms.83.3.495

  • Sakamoto K.

    Regulation of axonal regeneration and its inhibition by glycan ligands

    Trends in Glycoscience and Glycotechnology

    doi: https://doi.org/10.4052/tigg.2107.2E

  • Yamashita S., O. Kamatari Y., Honda R., Niwa A., Tomiata H., Hara A., Kuwata K.

    Monomeric a-synuclein (aS) inhibits amyloidogenesis of human prion protein (hPrP) by forming a stable aS-hPrP hetero-dimer.

    Prion

    doi: https://doi.org/10.1080/19336896.2021.1910176

  • Nakagawa Y., Yamaji F., Miyanishi W., Ojika M., Igarashi Y., Ito Y.

    Binding evaluation of pradimicins for oligomannose motifs from fungal mannans

    Bulletin of the Chemical Society of Japan

    doi: https://doi.org/10.1246/BCSJ.20200305

  • Yoshimura A., Asahina Y., Chang L.-Y., Angata T., Tanaka H., Kitajima K., Sato C.

    Identification and functional characterization of a Siglec-7 counter-receptor on K562 cells

    Journal of Biological Chemistry

    doi: https://doi.org/10.1016/j.jbc.2021.100477

  • Nakato M., Shiranaga N., Tomioka M., Watanabe H., Kurisu J., Kengaku M., Komura N., Ando H., Kimura Y., Kioka N., Ueda K.

    ABCA13 dysfunction associated with psychiatric disorders causes impaired cholesterol trafficking

    Journal of Biological Chemistry

    doi: https://doi.org/10.1074/jbc.RA120.015997

  • Kitano M., Kizuka Y., Sobajima T., Nakano M., Nakajima K., Misaki R., Itoyama S., Harada Y., Harada A., Miyoshi E., Taniguchi N.

    Rab11-mediated post-Golgi transport of the sialyltransferase ST3GAL4 suggests a new mechanism for regulating glycosylation

    Journal of Biological Chemistry

    doi: https://doi.org/10.1016/j.jbc.2021.100354

  • Oka N., Mori A., Suzuki K., Ando K.

    Stereoselective Synthesis of Ribofuranoid exo-Glycals by One-Pot Julia Olefination Using Ribofuranosyl Sulfones

    Journal of Organic Chemistry

    doi: https://doi.org/10.1021/acs.joc.0c02297

  • Yoshimura A., Hatanaka R., Tanaka H., Kitajima K., Sato C.

    The conserved arginine residue in all siglecs is essential for Siglec-7 binding to sialic acid

    Biochemical and Biophysical Research Communications

    doi: https://doi.org/10.1016/j.bbrc.2020.10.023

  • Hashimoto M., Fukamizu A., Nakagawa T., Kizuka Y.

    Roles of protein arginine methyltransferase 1 (PRMT1) in brain development and disease

    Biochimica et Biophysica Acta – General Subjects

    doi: https://doi.org/10.1016/j.bbagen.2020.129776

2020年

  • Higashi S.L., Hirosawa K.M., Suzuki K.G.N., Matsuura K., Ikeda M.

    One-Pot Construction of Multicomponent Supramolecular Materials Comprising Self-Sorted Supramolecular Architectures of DNA and Semi-Artificial Glycopeptides

    ACS Applied Bio Materials

    doi: https://doi.org/10.1021/acsabm.0c01316

  • Komura N., Suzuki K.G.N., Ando H., Konishi M., Hirose Y., Suganuma Y., Tanaka H.-N., Imamura A., Ishida H.

    Development of fluorescent ganglioside GD3 and Gq1b analogs for elucidation of raft-associated interactions

    Journal of Organic Chemistry

    doi: https://doi.org/10.1021/acs.joc.0c01493

  • Yagami N., Vibhute A.M., Tanaka H.-N., Komura N., Imamura A., Ishida H., Ando H.

    Stereoselective Synthesis of Diglycosyl Diacylglycerols with Glycosyl Donors Bearing a β-Stereodirecting 2,3-Naphthalenedimethyl Protecting Group

    Journal of Organic Chemistry

    doi: https://doi.org/10.1021/acs.joc.0c02121

  • Kitamura Y., Kandeel M., Kondo T., Tanaka A., Makino Y., Miyamoto N., Shibata A., Ikeda M., Kitade Y.

    Sulfonamide antibiotics inhibit RNAi by binding to human Argonaute protein 2 PAZ

    Bioorganic and Medicinal Chemistry Letters

    doi: https://doi.org/10.1016/j.bmcl.2020.127637

  • Higashi S.L., Rozi N., Hanifah S.A., Ikeda M.

    Supramolecular architectures of nucleic acid/peptide hybrids

    International Journal of Molecular Sciences

    doi: https://doi.org/10.3390/ijms21249458

  • Hirata T., Nagae M., Osuka R.F., Mishra S.K., Yamada M., Kizuka Y.

    Recognition of glycan and protein substrates by N-acetylglucosaminyltransferase-V

    Biochimica et Biophysica Acta – General Subjects

    doi: https://doi.org/10.1016/j.bbagen.2020.129726

  • Hashiguchi H., Tsukamoto Y., Ogawa M., Tashima Y., Takeuchi H., Nakamura M., Kawashima H., Fujishiro M., Okajima T.

    Glycoproteomic analysis identifies cryptdin-related sequence 1 as O-glycosylated protein modified with α1,2-fucose in the small intestine

    Archives of Biochemistry and Biophysics

    doi: https://doi.org/10.1016/j.abb.2020.108653

  • Yang Y., Murai R., Takahashi Y., Mori A., Hane M., Kitajima K., Sato C.

    Comparative studies of polysialic acids derived from five different vertebrate brains

    International Journal of Molecular Sciences

    doi: https://doi.org/10.3390/ijms21228593

  • Ertunc N., Sato C., Kitajima K.

    Sialic acid sulfation is induced by the antibiotic treatment in mammalian cells

    Bioscience, Biotechnology and Biochemistry

    doi: https://doi.org/10.1080/09168451.2020.1792763

  • Koyama-Honda I., Fujiwara T.K., Kasai R.S., Suzuki K.G.N., Kajikawa E., Tsuboi H., Tsunoyama T.A., Kusumi A.

    High-speed single-molecule imaging reveals signal transduction by induced transbilayer raft phases

    Journal of Cell Biology

    doi: https://doi.org/10.1083/JCB.202006125

  • Kawaguchi D., Kodama A., Abe N., Takebuchi K., Hashiya F., Tomoike F., Nakamoto K., Kimura Y., Shimizu Y., Abe H.

    Phosphorothioate Modification of mRNA Accelerates the Rate of Translation Initiation to Provide More Efficient Protein Synthesis

    Angewandte Chemie – International Edition

    doi: https://doi.org/10.1002/anie.202007111

  • Ma C., Takeuchi H., Hao H., Yonekawa C., Nakajima K., Nagae M., Okajima T., Haltiwanger R.S., Kizuka Y.

    Differential labeling of glycoproteins with alkynyl fucose analogs

    International Journal of Molecular Sciences

    doi: https://10.3390/ijms21176007

  • Mori A., Yang Y., Takahashi Y., Hane M., Kitajima K., Sato C.

    Combinational analyses with multiple methods reveal the existence of several forms of polysialylated neural cell adhesion molecule in mouse developing brains

    International Journal of Molecular Sciences

    doi: https://doi.org/10.3390/ijms21165892

  • Tomida H., Matsuhashi T., Tanaka H.-N., Komura N., Ando H., Imamura A., Ishida H.

    Indirect synthetic route to α-l-fucosides: Via highly stereoselective construction of α-l-galactosides followed by C6-deoxygenation

    Organic and Biomolecular Chemistry

    doi: https://doi.org/10.1039/d0ob01128b

  • Nobeyama T., Shigyou K., Nakatsuji H., Sugiyama H., Komura N., Ando H., Hamada T., Murakami T.

    Control of Lipid Bilayer Phases of Cell-Sized Liposomes by Surface-Engineered Plasmonic Nanoparticles

    Langmuir

    doi: https://doi.org/10.1021/acs.langmuir.0c00049

  • Tomida S., Takata M., Hirata T., Nagae M., Nakano M., Kizuka Y.

    The SH3 domain in the fucosyltransferase FUT8 controls FUT8 activity and localization and is essential for core fucosylation

    Journal of Biological Chemistrydoi:

    doi: https://doi.org/10.1074/JBC.RA120.013079

糖鎖生命コア研究所への
電話でのお問い合わせはこちら

052-789-5365

( 受付時間:平日 9:00-17:00 )

糖鎖生命コア研究所への
メールでのお問い合わせはこちら

Contact us

iGCORE パンフレット

iGCOREのパンフレット(PDFファイル)はこちらからダウンロードできます。