Elucidation of glycan functions by determining the structure of glycan and related molecules
The goal of Structural Analysis Division in the Integrated Glyco-Big Data Center (iGDATA) is to analyze the detailed structures of glycans and related molecules and to collect such information to elucidate glycan functions and develop glycan-targeted diagnoses. To achieve this, we perform structural analysis of glycans and related molecules from cells or tissue samples using MS. We utilize LC-MS, MALDI-MS, and NMR for this purpose. Additionally, we aim to develop novel technologies for automatic glycan analysis, enabling researchers to easily analyze glycan structures from multiple samples. With these approaches, we aim to obtain glycan information that can be useful for both disease diagnosis and a better understanding of life.